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Protein Overview: ATG23

General Information:
Name(s) found: ATG23 / YLR431C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Peripheral membrane protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway and efficient macroautophagy; cycles between the phagophore assembly site (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 453 amino acids

    Gene Ontology:
    Cellular Component: extrinsic to membrane [IDALink to PubMed article]
    Biological Process: autophagy [IMPLink to PubMed article]
    protein targeting to vacuole [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELNQVLEKK EQILQYLGTL VGLHEKALSD VNSASQVTSI RKDITICLND LCRINDLLVS  60
   61 HDGLLKREIG SLLRDKQELL ELNEREQLLW KERKSWHIKQ ETDAAPADYV IDKDAIITIS 120
  121 SHHRTSLNKY IESVGAENTI LSNTDDSDAM IEEVQNAESS ADQMIRNYKL LQLSHKQAKS 180
  181 EIIRLETLLR DFKKDNKFIE EELKRQSGRI RSEMGNIDFH LSKIEESKHQ LMKRIGFESP 240
  241 LTQEKSLSEK IFNLRLSSAD EDYNERQTIN MKNFVHMKDL IELKIEDLQE QLMRNKNESS 300
  301 TVLTQRELWL DCQKKVGDLE SKLITKLRSS SNSKIPPNEM SEMINSTIQY LNNLLDSSDE 360
  361 KLTTTLISNE RDVLSKACEE LHSESTTAQD GSSALPSKPI DIHKSHKGSN ASSNLKQPST 420
  421 PSFLVASKSP PKIGISESVV NANKNDAISK KVE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..122] PSI-BLAST 22.09691 Heavy meromyosin subfragment
    2 View Details [123..261] MSA 10.291997 View MSA. Confident ab initio structure predictions are available.
    3 View Details [262..453] PSI-BLAST 12.522879 Vimentin coil


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle