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Protein Overview: NIT3

General Information:
Name(s) found: NIT3 / YLR351C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKILSQK IKVALVQLSG SSPDKMANLQ RAATFIERAM KEQPDTKLVV LPECFNSPYS  60
   61 TDQFRKYSEV INPKEPSTSV QFLSNLANKF KIILVGGTIP ELDPKTDKIY NTSIIFNEDG 120
  121 KLIDKHRKVH LFDVDIPNGI SFHESETLSP GEKSTTIDTK YGKFGVGICY DMRFPELAML 180
  181 SARKGAFAMI YPSAFNTVTG PLHWHLLARS RAVDNQVYVM LCSPARNLQS SYHAYGHSIV 240
  241 VDPRGKIVAE AGEGEEIIYA ELDPEVIESF RQAVPLTKQR RFDVYSDVNA H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NIT3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..291] PSI-BLAST 1776.39794 hypothetical protein yl85

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.64442398754697 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.33107499649316 bayes_pls_golite062009
  • hydrolase activity
    		•  0.303336127811897 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle