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Protein Overview: TAD3

General Information:
Name(s) found: TAD3 / YLR316C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 322 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: tRNA modification [IDALink to PubMed article]
    Molecular Function: tRNA-specific adenosine deaminase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKVNNPLK IDYQNGIIEN RLLQIRNFKD VNTPKLINVW SIRIDPRDSK KVIELIRNDF  60
   61 QKNDPVSLRH LKRIRKDIET STLEVVLCSK EYICDEGEIN NKLKSIWVGT KKYELSDDIE 120
  121 VPEFAPSTKE LNNAWSVKYW PLIWNGNPND QILNDYKIDM QEVRNELSRA STLSVKMATA 180
  181 GKQFPMVSVF VDPSRKKDKV VAEDGRNCEN SLPIDHSVMV GIRAVGERLR EGVDEDANSY 240
  241 LCLDYDVYLT HEPCSMCSMA LIHSRVRRVV FLTEMQRTGS LKLTSGDGYC MNDNKQLNST 300
  301 YEAFQWIGEE YPVGQVDRDV CC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen LOS1 TAD3 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data TAD3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] deduced N/A No confident structure predictions are available.
    2 View Details [160..322] PSI-BLAST 20.0 Yeast cytosine deaminase crystal form p212121 with sodium acetate.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • binding
    		•  1.64474382695496 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.24697538679504 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.16679252289538 bayes_pls_golite062009
  • transferase activity
    		•  0.771056210634777 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.113989053833271 bayes_pls_golite062009
  • protein binding
    		•  0.072557222523031 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle