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Protein Overview: NEJ1

General Information:
Name(s) found: NEJ1 / YLR265C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 342 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: DNA repair [IDALink to PubMed article]
    double-strand break repair [IDALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSELKGQQL SDAEWCVKKI NGEGNCLLLF LPMSSPTTIV MIVLVSLERL VPYVFKLSQT  60
   61 QLSQQCQSQG FTDSISLNLI KLKLMDILQA PQEINQIGLV DSNLVFSFDV SADITVSINS 120
  121 VPSHVTKDMF YMILQSLCML LLKLVNLSTQ YHYVQRDILN EKQKCLDFLL ISLRDLDGGS 180
  181 KVISQWAPEN SKNYESLQQC TDDDIIKKLL HKGKFQHQEF LADSLKTLLS LRNKFQDVSR 240
  241 FEESGELNKK ERVRFPAVNH FYNDDFELQA DPTNEARPNS RGKIKPKTDF KPKSRESSTS 300
  301 SQLRLENFSE SEATPEKTKS SSSLVEEYPQ KKRKFGKVRI KN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BIO3 CIR1 NEJ1 ROD1 SOL4

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data NEJ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..342] deduced N/A No confident structure predictions are available.
    2 View Details [189..342] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle