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Protein Overview: HMX1

General Information:
Name(s) found: HMX1 / YLR205C [SGD]
Description(s) found:
Found 8 descriptions.
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  • ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 273 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: cellular iron ion homeostasis [IEPLink to PubMed article][ISSLink to PubMed article]
    heme catabolic process [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: peroxidase activity [IDALink to PubMed article]
    heme oxygenase (decyclizing) activity [IDALink to PubMed article][IEPLink to PubMed article][ISSLink to PubMed article]
    heme binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRHGFIYRQG ILAYYYVFDA IEQEIDRLLN DPVTEEELQT STILKQFWLE DFRRSTQIYK  60
   61 DLKLLYSNTF KSTESLNEFL ATFQKPPLLQ QFINNIHENI HKEPCTILSY CHVLYLALFA 120
  121 GGKLIRSNLY RRLGLFPNFE KLSQKELVKK GTNFFTFSDL GPTEETRLKW EYKKNYELAT 180
  181 RTELTEAQKL QIISVAEGIF DWNFNIVAEI GELNRRELMG KFSFKCITYL YEEWMFNKDS 240
  241 ATRRALHTVM LLVLSIIAIW VLYFLVKSFL SIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..273] PSI-BLAST 103.519517 No description for 1qq8A_ was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle