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Protein Overview: PUT1

General Information:
Name(s) found: PUT1 / YLR142W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    Biological Process: glutamate biosynthetic process [TASLink to PubMed article]
    proline catabolic process to glutamate [IMPLink to PubMed article][TASLink to PubMed article]
    Molecular Function: proline dehydrogenase activity [IMPLink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIASKSSLLV TKSRIPSLCF PLIKRSYVSK TPTHSNTAAN LMVETPAANA NGNSVMAPPN  60
   61 SINFLQTLPK KELFQLGFIG IATLNSFFLN TIIKLFPYIP IPVIKFFVSS LYCGGENFKE 120
  121 VIECGKRLQK RGISNMMLSL TIENSEGTKS LSSTPVDQIV KETISSVHNI LLPNIIGQLE 180
  181 SKPINDIAPG YIALKPSALV DNPHEVLYNF SNPAYKAQRD QLIENCSKIT KEIFELNQSL 240
  241 LKKYPERKAP FMVSTIDAEK YDLQENGVYE LQRILFQKFN PTSSKLISCV GTWQLYLRDS 300
  301 GDHILHELKL AQENGYKLGL KLVRGAYIHS EKNRNQIIFG DKTGTDENYD RIITQVVNDL 360
  361 IINGEDSYFG HLVVASHNYQ SQMLVTNLLK STQDNSYAKS NIVLGQLLGM ADNVTYDLIT 420
  421 NHGAKNIIKY VPWGPPLETK DYLLRRLQEN GDAVRSDNGW PLIKAIAKSI PKRVGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PUT1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] deduced N/A No confident structure predictions are available.
    2 View Details [107..476] Pfam 138.79588 Proline dehydrogenase No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  6.88732579226533 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  5.85999181868044 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  5.85251457886657 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.26500423104107 bayes_pls_golite062009
  • catalytic activity
    		•  2.15527229494088 bayes_pls_golite062009
  • methylenetetrahydrofolate reductase (NADPH) activity
    		•  1.53575450131902 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle