Protein Overview: GIS3

General Information:
Name(s) found:	GIS3 / YLR094C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6323123\|ref\|NP_013195.1\| Protein of unknown function; Gis3p [Saccharomyces cerevisiae] [NCBI NR] gi\|51315839\|sp\|Q12418.1\|GIS3_YEAST RecName: Full=Protein GIS3 [NCBI NR] gi\|51013041\|gb\|AAT92814.1\| YLR094C [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S64928 hypothetical protein YLR094c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1360471\|emb\|CAA97656.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1256844\|gb\|AAB67538.1\| Ylr094cp [Saccharomyces cerevisiae] [NCBI NR] Protein GIS3 OS=Saccharomyces cerevisiae GN=GIS3 PE=1 SV=1 [Swiss-Prot] GIS3 GIg1-2 Suppressor [mips] Protein of unknown function [SGD] GIS3, Chr XII from 327731-329239, reverse complement [yeast_orfs2] Chr XII from 327731-329239, reverse complement [yeastorf3.fasta] Chr XII from 329239-327731, reverse complement [yeastorf5.fasta] >Q12418 (Q12418) Chromosome XII reading frame ORF YLR094C [4932.FASTACCERV.txt] GIS3 SGDID:S0004084, Chr XII from 329239-327731, reverse complement, Verified ORF [yeastflysequest.fasta] Protein GIS3gi\|6323123\|ref\|NP_013195.1\| Gis3p [Saccharomyces cerevisiae]gi\|51013041\|gb\|AAT92814.1\| YLR094C [Saccharomyces cerevisiae]gi\|1360471\|emb\|CAA97656.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1256844\|gb\|AAB67538.1\| Ylr094cp [Sacch [nrdb_11152004_Chlamydomonas] (Q12418) Protein GIS3 [cerv4932.FASTAC] GIS3 SGDID:S000004084, Chr XII from 329239-327731, reverse complement, Verified ORF, "Protein of unknown function" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein of unknown function; Gis3p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ylr094cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YLR094C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein GIS3 [nr-271106-contam.fasta] [chemostatdb.fasta] Protein GIS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GIS3 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] GIS3 SGDID:S000004084, Chr XII from 329238-327730, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function" [yeast-030211-contam.fasta] GIS3 SGDID:S000004084, Chr XII from 329238-327730, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein of unknown function" [20141208_orf_trans.fasta] TR6339\|c0_g1_i1\|g.4489 ORF TR6339\|c0_g1_i1\|g.4489 TR6339\|c0_g1_i1\|m.4489 type:complete len:503 (+) TR6339\|c0_g1_i1:120-1628(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR8409\|c0_g1_i1\|g.5995 ORF TR8409\|c0_g1_i1\|g.5995 TR8409\|c0_g1_i1\|m.5995 type:complete len:503 (+) TR8409\|c0_g1_i1:120-1628(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YLR094C SGDID:S000004084, Chr XII from 329238-327730, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_8387\|g.6147 ORF asmbl_8387\|g.6147 asmbl_8387\|m.6147 type:complete len:503 (+) asmbl_8387:119-1627(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_8630\|g.6323 ORF asmbl_8630\|g.6323 asmbl_8630\|m.6323 type:complete len:503 (+) asmbl_8630:119-1627(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_8537\|g.5204 ORF ID=asmbl_8537\|g.5204 ID=asmbl_8537\|m.5204 type:complete len:503 (+) ID=asmbl_8537:119-1627(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_8630\|g.5237 ORF ID=asmbl_8630\|g.5237 ID=asmbl_8630\|m.5237 type:complete len:503 (+) ID=asmbl_8630:119-1627(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	502 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	intracellular signaling pathway [IGI] response to water [RCA]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLDVNTNHT LMHDAHVHEH CLIKSIRDDG ALHSWSDSSK VFYPKSFYAT ATNKKNNKLA  60
   61 SASMNKTATS NRTVSDEIYF HSTKPQFDGQ GSAERTRTLT KRNSFKRTRI LKARDDSELL 120
  121 NENRSSLMTP SLSSVMSQVR KTNSAKTLSG ECPIHEGHLT QSIKRKFSEE AQSDCSSLSS 180
  181 SKLHPLTDDI ADAVDLQTPA IGDEVLAEPV VPKMKIININ DLDLFDDWEV KDLVDIFPPV 240
  241 YERRPRSSSA LSLVSASSDA KLRPTSVDFQ IIDKKGGKTS RRKSRSKSTT ENMIYENDLV 300
  301 ELEQWPSASP SPETDGSIAS SELLPNKRIR QKSLNTNFLK LYSIETSCKR KSILPEVEVD 360
  361 DHLLKQLTYS EIRSLEIKKE PNVSTNDIKL ALITRKKLWS DMVHETRNDL FGDSTPWNLH 420
  421 FVATTSNTEP SQGRESASEH ATADLKSSLV RVHSDVKPWF NNGGTMLKPC GKLNLGKVTN 480
  481 KTSAPTREIQ YVVKGWCDSR FL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	HBT1	GIS3	2	Unpublished Fields Lab Data
View Screen	MPC54	GIS3	2	Unpublished Fields Lab Data
View Screen	IML1	GIS3	2	Unpublished Fields Lab Data
View Screen	CAB3	GIS3	2	Unpublished Fields Lab Data
View Screen	SPO21	GIS3	2	Unpublished Fields Lab Data
View Screen	CDC13	GIS3	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	GIS3	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..275]	MSA	1.002883	View MSA. No confident structure predictions are available.
2	View Details	[276..502]	deduced	N/A	No confident structure predictions are available.
3	View Details	[228..296]	deduced	N/A	No confident structure predictions are available.
4	View Details	[297..502]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2