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Protein Overview: JLP1

General Information:
Name(s) found: JLP1 / YLL057C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: sulfur metabolic process [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: sulfonate dioxygenase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPAAAQTAI PLPSTDLPVK IITNGLKNLN YTSKQGYGNF DTHFYDGQDE VSPSGLLKIR  60
   61 KSYREKSKYP DYLPTWDPTE KYGPLEFHEY HDPALRADGN FSNLFAKENV GQLKVKKITP 120
  121 KLGLEINGIQ LTDLSDAAKD ELALLVAQKG VVVFRNQNFA DEGPDYVTEY GRHFGKLHIH 180
  181 QTSGHPQNNP ELHITFRRPD AEEFARVFDD STSSGGWHTD VSYELQPPSY TFFSVVEGPD 240
  241 GGGDTLFADT IEAFDRLSKP LQDFLSTLHV IHSSKEQAEN SQRQGGIKRR APVTHIHPLV 300
  301 RVHPVLKKKC LYVNRAFSRK IVELKRQESE SLLNFLYNLV ESSHDLQLRA KWEPHSVVIW 360
  361 DNRRVQHSAV IDWEEPIHRH AFRITPQAER PVEDLKFLND ENYYPSSLTL DI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] deduced N/A No confident structure predictions are available.
    2 View Details [92..249]
    [344..388]    		 PSI-BLAST 386.522879 Taurine/alpha-ketoglutarate dioxygenase
    3 View Details [250..343]
    [389..412]    		 PSI-BLAST 386.522879 Taurine/alpha-ketoglutarate dioxygenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
    		•  1.45256699472411 bayes_pls_golite062009
  • catalytic activity
    		•  0.921320409505 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.700777872792887 bayes_pls_golite062009
  • binding
    		•  0.525807098218081 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  0.15567515806758 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle