YRC Public Data Repository - Protein Structure Prediction

Protein:	JLP1
Organism:	Saccharomyces cerevisiae
Length:	412 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JLP1.

Description	E-value	Query Range	Subject Range
gi\|151941116 - gi\|151941116\|gb\|EDN59494.1\| dnaJ-like protein [Saccharomyces cerevisiae YJM789] JLP1_YEAST - Alpha-ketoglutarate-dependent sulfonate dioxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 ... JLP1 - Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use...	0.0	[1..412]	[1..412]
gi\|189373761, gi... - gi\|189373761\|gb\|EDU92177.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC869], gi\|168786201\|... gi\|188999387, gi... - gi\|188999387\|gb\|EDU68373.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4076], gi\|168783221... gi\|169756183, gi... - gi\|170021255\|ref\|YP_001726209.1\| taurine dioxygenase [Escherichia coli ATCC 8739], gi\|169756183\|gb\|A... gi\|168800238, gi... - gi\|189377380\|gb\|EDU95796.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC508], gi\|168800238\|... gi\|208726398, gi... - gi\|208806597\|ref\|ZP_03248934.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|13359879, gi\|... - gi\|15829676\|ref\|NP_308449.1\| taurine dioxygenase [Escherichia coli O157:H7 str. Sakai], gi\|13359879\|... gi\|195938569 - gi\|195938569\|ref\|ZP_03083951.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4024] gi\|124528915, gi... - gi\|124528915\|ref\|ZP_01700100.1\| Taurine dioxygenase [Escherichia coli B], gi\|124500252\|gb\|EAY47728.1... gi\|208822961, gi... - gi\|208822961\|ref\|ZP_03263279.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|208815909, gi... - gi\|208815909\|ref\|ZP_03257088.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|188015925, gi... - gi\|188015925\|gb\|EDU54047.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4113], gi\|168749818... gi\|189368052, gi... - gi\|189368052\|gb\|EDU86468.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4501], gi\|168761560... gi\|168756897, gi... - gi\|189355960\|gb\|EDU74379.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4401], gi\|168756897... gi\|168776339, gi... - gi\|187768267\|gb\|EDU32111.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4196], gi\|168776339... gi\|189362420, gi... - gi\|189362420\|gb\|EDU80839.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4486], gi\|168768306... gi\|209744492, gi... - pir\|\|B85532 taurine dioxygenase, 2-oxoglutarate-dependent [imported] - Escherichia coli (strain O157... gi\|15800098, gi\|... - gi\|15800098\|ref\|NP_286110.1\| taurine dioxygenase [Escherichia coli O157:H7 EDL933], gi\|12513209\|gb\|A... gi\|13359879, gi\|... - gi\|15829676\|ref\|NP_308449.1\| taurine dioxygenase [Escherichia coli O157:H7], gi\|13359879\|dbj\|BAB3384... gi\|217325762, gi... - gi\|217325762\|ref\|ZP_03441846.1\| taurine dioxygenase [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|209160608, gi... - gi\|209399208\|ref\|YP_002269009.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4115], gi\|2091... tr\|A0A0X8UG71\|A0... - Taurine dioxygenase OS=Escherichia coli (strain K12) GN=tauD PE=4 SV=1 gi\|242376150, gi... - gi\|251783877\|ref\|YP_002998181.1\| hypothetical protein B21_00322 [Escherichia coli BL21], gi\|24237615... gi\|194422154, gi... - gi\|83585708\|ref\|ZP_00924350.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli 10... gi\|253774647, gi... - gi\|254287240\|ref\|YP_003052988.1\| taurine dioxygenase [Escherichia coli BL21(DE3)], gi\|253976547\|gb\|A... gi\|254160437, gi... - gi\|254160437\|ref\|YP_003043545.1\| taurine dioxygenase [Escherichia coli B str. REL606], gi\|253972338\|... gi\|254590948, gi... - gi\|254791548\|ref\|YP_003076385.1\| taurine dioxygenase, 2-oxoglutarate-dependent [Escherichia coli O15...	8.0E-66	[110..395]	[2..282]
gi\|238899661, gi... - gi\|238899661\|ref\|YP_002925457.1\| taurine dioxygenase, 2-oxoglutarate-dependent [Escherichia coli BW2... EG12423 - taurine dioxygenase, 2-oxoglutarate-dependent / Taurine /alpha-ketoglutarate dioxygenase gi\|188496113, gi... - gi\|75512431\|ref\|ZP_00734970.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli 53... gi\|89107239, gi\|... - gi\|89107239\|ref\|AP_001019.1\| taurine dioxygenase, 2-oxoglutarate-dependent [Escherichia coli str. K-... TAUD_ECOLI - Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) (2-aminoethanesulfonate dioxygenas... EG12423 - taurine dioxygenase, 2-oxoglutarate-dependent / Taurine /alpha-ketoglutarate dioxygenase gi\|170079957, gi... - gi\|170079957\|ref\|YP_001729277.1\| taurine dioxygenase, 2-oxoglutarate-dependent [Escherichia coli str... gi\|170683535, gi... - gi\|170683535\|ref\|YP_001742500.1\| taurine dioxygenase [Escherichia coli SMS-3-5], gi\|170521253\|gb\|ACB...	1.0E-65	[110..395]	[2..282]
gi\|149290172, gi... - gi\|150260764\|ref\|ZP_01917492.1\| putative taurine dioxygenase [Yersinia pestis CA88-4125], gi\|1492901... gi\|145209127, gi... - gi\|145597431\|ref\|YP_001161506.1\| taurine dioxygenase [Yersinia pestis Pestoides F], gi\|145209127\|gb\|... gi\|161511470 - gi\|161511470\|ref\|NP_991584.2\| taurine dioxygenase [Yersinia pestis biovar Microtus str. 91001] gi\|161484725 - gi\|161484725\|ref\|NP_671259.2\| taurine dioxygenase [Yersinia pestis KIM] gi\|162420117, gi... - gi\|77634624\|ref\|ZP_00796721.1\| COG2175: Probable taurine catabolism dioxygenase [Yersinia pestis Ang... gi\|165990611, gi... - gi\|166010521\|ref\|ZP_02231419.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|153947413, gi... - gi\|77631162\|ref\|ZP_00793748.1\| COG2175: Probable taurine catabolism dioxygenase [Yersinia pseudotube... gi\|165920109, gi... - gi\|165927833\|ref\|ZP_02223665.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|167399106, gi... - gi\|167399106\|ref\|ZP_02304630.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|166205443, gi... - gi\|166213145\|ref\|ZP_02239180.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|218927394, gi... - gi\|218927394\|ref\|YP_002345269.1\| taurine dioxygenase [Yersinia pestis CO92], gi\|16120526\|ref\|NP_4038... gi\|108814042, gi... - gi\|229904575\|ref\|ZP_04519686.1\| putative taurine dioxygenase [Yersinia pestis Nepal516], gi\|22967869... gi\|51591291, gi\|... - gi\|51598009\|ref\|YP_072200.1\| taurine dioxygenase [Yersinia pseudotuberculosis IP 32953], gi\|51591291... Q664Q0\|Q664Q0_YERPS - Putative taurine dioxygenase - Yersinia pseudotuberculosis gi\|89103007, gi\|... - gi\|89103007\|ref\|ZP_01175605.1\| COG2175: Probable taurine catabolism dioxygenase [Yersinia pestis bio... gi\|108781191, gi... - gi\|108809278\|ref\|YP_653194.1\| taurine dioxygenase [Yersinia pestis Antiqua], gi\|108781191\|gb\|ABG1524... gi\|167425659, gi... - gi\|167425659\|ref\|ZP_02317412.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|166962823, gi... - gi\|167418829\|ref\|ZP_02310582.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis b... gi\|169749056, gi... - gi\|170022522\|ref\|YP_001719027.1\| taurine dioxygenase [Yersinia pseudotuberculosis YPIII], gi\|1697490... gi\|167468833 - gi\|167468833\|ref\|ZP_02333537.1\| alpha-ketoglutarate-dependent taurine dioxygenase [Yersinia pestis F... gi\|186700231, gi... - gi\|186897205\|ref\|YP_001874317.1\| taurine dioxygenase [Yersinia pseudotuberculosis PB1/+], gi\|1867002... gi\|229706401, gi... - gi\|229836333\|ref\|ZP_04456500.1\| putative taurine dioxygenase [Yersinia pestis Pestoides A], gi\|22970... gi\|229840043, gi... - gi\|229840043\|ref\|ZP_04460202.1\| putative taurine dioxygenase [Yersinia pestis biovar Orientalis str.... gi\|229842125, gi... - gi\|229842125\|ref\|ZP_04462280.1\| putative taurine dioxygenase [Yersinia pestis biovar Orientalis str.... gi\|25351103 - pir\|\|AE0023 probable taurine dioxygenase tauD [imported] - Yersinia pestis (strain CO92)	2.0E-65	[111..395]	[3..282]
TFDA_ALCEU - (P10088) Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase (EC 1.14.11.-) (2,4-D ... gi\|141977 - gi\|141977\|gb\|AAA21983.1\| 2,4-dichlorophenoxyacetate monooxygenase (gtg start codon) gi\|194245741 - gi\|194245741\|gb\|ACF35489.1\| TfdA [Burkholderia sp. TFD19] gi\|194245743 - gi\|194245743\|gb\|ACF35490.1\| TfdA [Cupriavidus sp. TFD33] gi\|194245745 - gi\|194245745\|gb\|ACF35491.1\| TfdA [Cupriavidus sp. TFD38] gi\|194245747 - gi\|194245747\|gb\|ACF35492.1\| TfdA [Pseudomonas sp. TFD39] TFDA_CUPPJ - Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase OS=Cupriavidus pinatubonensis (... gi\|194245749 - gi\|194245749\|gb\|ACF35493.1\| TfdA [Pseudomonas sp. TFD51]	1.0E-64	[112..392]	[2..287]
gi\|194245731 - gi\|194245731\|gb\|ACF35484.1\| TfdA [Pseudomonas sp. TFD50] gi\|194245729 - gi\|194245729\|gb\|ACF35483.1\| TfdA [Pseudomonas putida] gi\|194245727 - gi\|194245727\|gb\|ACF35482.1\| TfdA [Cupriavidus respiraculi] gi\|15026872 - gi\|15026872\|gb\|AAK81681.1\| 2,4-D/alpha-ketoglutarate dioxygenase [Burkholderia cepacia] gi\|194245725 - gi\|194245725\|gb\|ACF35481.1\| TfdA [Cupriavidus sp. TFD40] gi\|194245723 - gi\|194245723\|gb\|ACF35480.1\| TfdA [Cupriavidus sp. TFD45] gi\|194245721 - gi\|194245721\|gb\|ACF35479.1\| TfdA [Variovorax koreensis]	1.0E-63	[112..392]	[2..287]
TFDA_BURSR - Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase OS=Burkholderia sp. (strain RAS...	1.0E-63	[112..396]	[2..291]
gi\|28923217, gi\|... - gi\|32412139\|ref\|XP_326550.1\| predicted protein [Neurospora crassa], gi\|28923217\|gb\|EAA32433.1\| conse... gi\|85104107 - gi\|85104107\|ref\|XP_961669.1\| hypothetical protein NCU01057 [Neurospora crassa OR74A]	5.0E-63	[31..387]	[21..372]
ATSK_PSEPU - Alpha-ketoglutarate-dependent sulfate ester dioxygenase OS=Pseudomonas putida GN=atsK PE=1 SV=1	1.0E-62	[102..392]	[4..288]
gi\|11349512 - pir\|\|F83356 hypothetical protein PA2310 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|9948343, gi\|1... - gi\|9948343\|gb\|AAG05698.1\|AE004657_5 hypothetical protein PA2310 [Pseudomonas aeruginosa PAO1], gi\|15... gi\|218771942, gi... - gi\|218891716\|ref\|YP_002440583.1\| putative taurine catabolism dioxygenase [Pseudomonas aeruginosa LES... gi\|194546305, gi... - gi\|254235320\|ref\|ZP_04928643.1\| hypothetical protein PACG_01220 [Pseudomonas aeruginosa C3719], gi\|1...	1.0E-61	[112..391]	[14..294]

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Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPAAAQTAI PLPSTDLPVK IITNGLKNLN YTSKQGYGNF DTHFYDGQDE VSPSGLLKIR  60
   61 KSYREKSKYP DYLPTWDPTE KYGPLEFHEY H

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [92-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPALRADGNF SNLFAKENVG QLKVKKITPK LGLEINGIQL TDLSDAAKDE LALLVAQKGV  60
   61 VVFRNQNFAD EGPDYVTEYG RHFGKLHIHQ TSGHPQNNPE LHITFRRPDA EEFARVFDDS 120
  121 TSSGGWHTDV SYELQPPSYT FFSVVEGPDG GGDTLFAD

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [344-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDLQLRAKWE PHSVVIWDNR RVQHSAVIDW EEPIHRHAFR ITPQA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	386.522879
Match:	1gy9A_
Description:	Taurine/alpha-ketoglutarate dioxygenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.45256699472411	bayes_pls_golite062009
catalytic activity	0.921320409505	bayes_pls_golite062009
oxidoreductase activity	0.700777872792887	bayes_pls_golite062009
binding	0.525807098218081	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.15567515806758	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [250-343]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIEAFDRLSK PLQDFLSTLH VIHSSKEQAE NSQRQGGIKR RAPVTHIHPL VRVHPVLKKK  60
   61 CLYVNRAFSR KIVELKRQES ESLLNFLYNL VESS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [389-412]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERPVEDLKFL NDENYYPSSL TLDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	386.522879
Match:	1gy9A_
Description:	Taurine/alpha-ketoglutarate dioxygenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: