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Protein Overview: YLL017W

General Information:
Name(s) found: YLL017W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Non-essential Ras guanine nucleotide exchange factor (GEF) localized to the membrane; expressed in poor nutrients and on non-fermentable carbon sources; homologous to CDC25; contains a stop codon in S288C; full-length gene includes YLL016W [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 103 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDALink to PubMed article]
    Biological Process: Ras protein signal transduction [TASLink to PubMed article]
    Molecular Function: Ras guanyl-nucleotide exchange factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCTASYAGM TTPVKDKEGH GIPCLQPIDV VECTYQYFTK SRNKLSLRVG DLIYVLTKGS  60
   61 NGWWDGVLIR HSANNNNNSL ILDRGWFPPS FYTVHSKRTT RGA

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ERI1 YLL017W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 20.69897 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.375837873453985 bayes_pls_golite062009
  • protein binding
    		•  0.25580402341401 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle