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Protein Overview: ECM4

General Information:
Name(s) found: ECM4 / YKR076W [SGD]
Description(s) found:
Found 27 descriptions.
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  • Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: glutathione metabolic process [ISSLink to PubMed article]
    cellular cell wall organization [IMPLink to PubMed article]
    Molecular Function: glutathione transferase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQWASGTN GAFKRQVSSF RETISKQHPI YKPAKGRYWL YVSLACPWAH RTLITRALKG  60
   61 LTSVIGCSVV HWHLDEKGWR FLDMEKQLED SEDFLEHWHD VAGGIRTAKE DSSKSFAEIK 120
  121 NDSQRFMVDA TNEPHYGYKR ISDLYYKSDP QYSARFTVPV LWDLETQTIV NNESSEIIRI 180
  181 LNSSAFDEFV DDDHKKTDLV PAQLKTQIDD FNSWVYDSIN NGVYKTGFAE KAEVYESEVN 240
  241 NVFEHLDKVE KILSDKYSKL KAKYGEEDRQ KILGEFFTVG DQLTEADIRL YTTVIRFDPV 300
  301 YVQHFKCNFT SIRAGYPFIH LWVRNLYWNY DAFRYTTDFD HIKLHYTRSH TRINPLGITP 360
  361 LGPKPDIRPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ECM4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] ORFEUS 14.99 Class omega GST
    2 View Details [199..370] ORFEUS 14.99 Class omega GST

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione binding
    		•  1.77211489459567 bayes_pls_golite062009
  • glutathione transferase activity
    		•  1.4787810404032 bayes_pls_golite062009
  • antioxidant activity
    		•  1.3961148524753 bayes_pls_golite062009
  • peroxidase activity
    		•  1.2460437903417 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  1.2460437903417 bayes_pls_golite062009
  • binding
    		•  1.18507788580647 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.699008336089393 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  0.651680638869122 bayes_pls_golite062009
  • catalytic activity
    		•  0.646676412582618 bayes_pls_golite062009
  • protein binding
    		•  0.376412693567268 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle