YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FRE2

General Information:
Name(s) found: FRE2 / YKL220C [SGD]
Description(s) found:
Found 27 descriptions.
SHOW ALL
  • Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 711 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article]
    Biological Process: iron ion transport [IDALink to PubMed article]
    copper ion import [IDALink to PubMed article]
    Molecular Function: ferric-chelate reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHWTSILSAI LLFCLSGARA SPAKTVIRNK VPLLVTNACT RIFQKVTWEY TSKSKRSSPV  60
   61 CSYEPAFQSM LYCIYETLDE KGYSNKTLEK TFSTIKKNCA SYSDALQNMT NSEFYDVLNN 120
  121 GTRHMTPYVK GSANLTYPVE MDTQLRKAYY HALHGFYANL DVGNIYGGII CAYFVAIMAF 180
  181 AGVLHCMNYT PFKTVLLKQK LVGYVRGYLT LPTIGSKHAS DFSYFRIFTG YLPTRLEGII 240
  241 ILGYLVLHTV FLAYGYEYDP ENIIFKSRRV QVARYVADRS GVLAFAHFPL IVLFAGRNNF 300
  301 LEYISGVKYT SFIMFHKWLG RMMFLDAMIH GSAYTSYTVA NKTWATSKNR LYWQFGVAAL 360
  361 CLAGTMVFFS FAVFRKYFYE AFLFLHIVLG AMFFYACWEH VVSLSGIEWI YTAIAIWIVD 420
  421 RIIRIIKASY FGFPKASLQL IGDDLIRLTV KKPARPWRAK PGQYVFVSFL HPLYFWQSHP 480
  481 FTVLDSVSKN GELVIILKEK KGVTRLVKKY VCRNGGKTSM RLAIEGPYGS SSPVNNYNNV 540
  541 LLLTGGTGLP GPIAHAIKLG KTSAAAGKQS VKLVIAVRGF DVLEAYKPEL MCLENLNVQL 600
  601 HIYNTMEVPS LTPSDSLDIS QQDEKADEKG TVVATTLEKS ANPLGFDGVV FHCGRPNVKE 660
  661 LLHEAAELSG SLSVVCCGPP IFVDKVRNET AKIVLDKSAK AIEYFEEYQC W

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) FET3 FRE1 FRE2 FRE4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NTA1 FRE2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] MSA 1.05098 View MSA. No confident structure predictions are available.
    2 View Details [219..344] MSA 2.079986 View MSA. No confident structure predictions are available.
    3 View Details [345..405] deduced N/A Confident ab initio structure predictions are available.
    4 View Details [406..528] PSI-BLAST 53.0 Nitrate reductase core domain; Nitrate reductase
    5 View Details [529..711] PSI-BLAST 53.0 Nitrate reductase core domain; Nitrate reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • catalytic activity
    		•  1.45374095556065 bayes_pls_golite062009
  • transferase activity
    		•  1.15480450573972 bayes_pls_golite062009
  • binding
    		•  1.13408475648113 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.27336340260908 bayes_pls_golite062009
  • protein binding
    		•  0.144900113694048 bayes_pls_golite062009
  • cofactor binding
    		•  0.0731141170494622 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle