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Protein Overview: MIA40

General Information:
Name(s) found: MIA40 / YKL195W [SGD]
Description(s) found:
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  • gi|549742|sp|P36046|YKT5_YEAST Hypothetical 47.4 kDa protein in PAS1-MST1 intergenic region [NCBI NR]
  • pir||S38032 hypothetical protein YKL195w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|486347|emb|CAA82039.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • (P36046) Hypothetical 47.4 kDa protein in PAS1-MST1 intergenic region [Swiss-Prot]
  • similarity to rabbit histidine-rich calcium-binding protein [mips]
  • Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins [SGD]
  • YKL195W, Chr XI from 75751-77034 [yeast_orfs2]
  • Chr XI from 75751-77034 [yeastorf3.fasta]
  • Chr XI from 75750-77033 [yeastorf4.fasta]
  • unnamed protein product [Saccharomyces cerevisiae]gi|539215|pir||S38032 hypothetical protein YKL195w - yeast (Saccharomyces cerevisiae)gi|549742|sp|P36046|YKT5_YEAST Hypothetical 47.4 kDa protein in PAS1-MST1 intergenic region [nrdb_11152004_Chlamydomonas]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 427 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    mitochondrial outer membrane translocase complex [IDALink to PubMed article]
    Biological Process: protein import into mitochondrial intermembrane space [IMPLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    protein targeting [IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLWNTNYQ LEVGSIQRVY IISKMLRNLV VRNACRNRPS IQVARGLCRH QTRRLMASSP  60
   61 QFGRNSNQEK TAGFIMGILS MAGALYFIAP NRKPLFASRK VESDKTAEEE LSSGGEQSPE 120
  121 NEDDNNSKSD ENGDDNDSKN DETEAGPQLG GDKIGASKVA EDGELVVLAE EDNKSSEDKD 180
  181 TDESKVSTKD DEQSNEDNAT ANNQKDENIS SENSEENTSD KTLDNNAGSS EKKDPEHSDD 240
  241 EKSQQGQSDD KTTTEDNNGE EESSKKTVSD SENSAKQSES SDEEKEELRK QEEKQMGPTE 300
  301 EEVQHEGAYN PDTGEINWDC PCLGGMAHGP CGEEFKSAFS CFVYSEAEPK GIDCVEKFQH 360
  361 MQDCFRKYPE HYAEQLKETS DDEEPQDKVK VNTIESAPNV SSAKENAAKK AEQSDVKKEP 420
  421 LNEESKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIA40 No Comments Hazbun TR, et al. (2003)
    View Run MIA40 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..427] MSA 19.187997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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