Protein Overview: MTR2

General Information:
Name(s) found:	MTR2 / YKL186C [SGD]
Description(s) found: Found 34 descriptions. SHOW ALL	mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA [SGD]
Organism:	Saccharomyces cerevisiae
Length:	184 amino acids
Gene Ontology:
Cellular Component:	nuclear pore [IDA]
Biological Process:	poly(A)+ mRNA export from nucleus [IMP ][IPI]
Molecular Function:	protein binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTNSNTMVM NDANQAQITA TFTKKILAHL DDPDSNKLAQ FVQLFNPNNC RIIFNATPFA  60
   61 QATVFLQMWQ NQVVQTQHAL TGVDYHAIPG SGTLICNVNC KVRFDESGRD KMGQDATVPI 120
  121 QPNNTGNRNR PNDMNKPRPL WGPYFGISLQ LIIDDRIFRN DFNGVISGFN YNMVYKPEDS 180
  181 LLKI

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		MTR2 NUP1 SUS1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RPC19	MTR2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	MTR2	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..184]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
nucleocytoplasmic transporter activity	4.11811310168752	bayes_pls_golite062009
protein transporter activity	3.25560675565407	bayes_pls_golite062009
protein transmembrane transporter activity	2.19585939185279	bayes_pls_golite062009
binding	1.93127150192473	bayes_pls_golite062009
transporter activity	1.80701285041353	bayes_pls_golite062009
protein binding	1.74084472095013	bayes_pls_golite062009
nucleic acid binding	1.64945646555286	bayes_pls_golite062009
substrate-specific transporter activity	1.33804818542017	bayes_pls_golite062009
structural constituent of nuclear pore	1.30758304562723	bayes_pls_golite062009
transmembrane transporter activity	1.22102896992563	bayes_pls_golite062009
Ran GTPase binding	1.18290069522408	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.890150150408175	bayes_pls_golite062009
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	0.85112284161201	bayes_pls_golite062009
macromolecule transmembrane transporter activity	0.85112284161201	bayes_pls_golite062009
RNA binding	0.60026322125847	bayes_pls_golite062009
primary active transmembrane transporter activity	0.446562877324676	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.439519001457896	bayes_pls_golite062009
active transmembrane transporter activity	0.430285640125175	bayes_pls_golite062009
protein kinase activity	0.385097965690479	bayes_pls_golite062009
protein serine/threonine kinase activity	0.349622123487291	bayes_pls_golite062009
mRNA binding	0.15644148341628	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2