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Protein Overview: CSE4

General Information:
Name(s) found: CSE4 / YKL049C [SGD]
Description(s) found:
Found 8 descriptions.
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  • Centromere protein that resembles histone H3, required for proper kinetochore function; homolog of human CENP-A [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 137 amino acids

    Gene Ontology:
    Cellular Component: condensed nuclear chromosome, centromeric region [IGILink to PubMed article]
    extrachromosomal circular DNA [IDALink to PubMed article]
    nuclear nucleosome [IDALink to PubMed article]
    kinetochore [IGILink to PubMed article]
    Biological Process: mitotic sister chromatid segregation [IMPLink to PubMed article]
    2-micrometer plasmid partitioning [IMPLink to PubMed article]
    Molecular Function: sequence-specific DNA binding [IDALink to PubMed article]
    centromeric DNA binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METEVPAPVR THSYALDRYV RQKRREKQRK QSLKRVEKKY TPSELALYEI RKYQRSTDLL  60
   61 ISKIPFARLV KEVTDEFTTK DQDLRWQSMA IMALQEASEA YLVGLLEHTN LLALHAKRIT 120
  121 IMKKDMQLAR RIRGQFI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIF2 No Comments Cheeseman IM, et al. (2002)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..137] PSI-BLAST 288.54902 Histone H3


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle