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Protein Overview: GPX1

General Information:
Name(s) found: GPX1 / YKL026C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 167 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: response to oxidative stress [IMPLink to PubMed article]
    Molecular Function: phospholipid-hydroperoxide glutathione peroxidase activity [IDALink to PubMed article][IMPLink to PubMed article]
    glutathione peroxidase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEFYSFSPI DENGNPFPFN SLRNKVVLIV NVASHCAFTP QYKELEYLYE KYKSHGLVIV  60
   61 AFPCGQFGNQ EFEKDKEINK FCQDKYGVTF PILHKIRCNG QKQDPVYKFL KNSVSGKSGI 120
  121 KMIKWNFEKF VVDRNGKVVK RFSCMTRPLE LCPIIEELLN QPPEEQI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data GPX1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..167] PSI-BLAST 205.39794 Glutathione peroxidase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle