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Protein Overview: MPH3

General Information:
Name(s) found: MPH3 / YJR160C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 602 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [ISSLink to PubMed article]
    Biological Process: carbohydrate transport [IDALink to PubMed article][ISSLink to PubMed article]
    Molecular Function: carbohydrate transmembrane transporter activity [ISSLink to PubMed article]
    phosphoribosylanthranilate isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNLSFLINR RKENTSDSNV YPGKAKSHEP SWIEMDDQTK KDGLDIVHVE FSPDTRAPSD  60
   61 SNKVITEIFD ATEDAKEADE SERGMPLATA LNTYPKAAAW SLLVSTTLIM EGYDTAILGA 120
  121 FYALPIFQRK FGSQNDKTGE WEISASWQIG LTLCYMAGEI VGLQLTGPSV DLVGNRYTLI 180
  181 IALFFLAAFT FILYFCNSLG MIAVGQALCG MPWGCFQCLT VSYASEICPL ALRYYLTTYS 240
  241 NLCWLFGQLF AAGIMKNSQK KYADSELGYK LPFALQWILP VPLALGIFFA PESPWWLVKK 300
  301 GRFDEARRSL RRTLSGKGPE KEILVTLEVD KIKVTIDKEK RLTSKEGSYS DCFEDKINRR 360
  361 RTRITCLCWA GQATCGSILI GYSTYFYEKA GVSTEMSFTF SIIQYCLGIC ATFLSWWASK 420
  421 YFGRYDLYAF GLAFQTIVFF IIGGLGCSST HGSKMGSGSL LMAVAFFYNL GIAPVVFCLV 480
  481 SEMPSSRLRT KTIILARNTY NVVSIICSVL ILYQLNSKKW NWGAKSGFFW GVLCFCTLIW 540
  541 AVVDLPETAG KTFVEINELF KLGVSARKFK STKVDPFVVK TPPKDVSHND PKGDIEASIA 600
  601 EE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) HXT11 MPH3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [69..291]
    [344..549]    		 PSI-BLAST 196.228787 No description for 1ja5A_ was found.
    3 View Details [292..343]
    [550..602]    		 PSI-BLAST 196.228787 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • binding
    		•  0.873217664940684 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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