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Protein Overview: PFD1

General Information:
Name(s) found: PFD1 / YJL179W [SGD]
Description(s) found:
Found 17 descriptions.
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  • Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 109 amino acids

    Gene Ontology:
    Cellular Component: prefoldin complex [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: cytoskeleton organization [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed article]
    protein folding [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: unfolded protein binding [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQIAQEMTV SLRNARTQLD MVNQQLAYLD RQEKLAELTK KELESYPTDK VWRSCGKSFI  60
   61 LQDKSKYVND LSHAETVLLD QRKTLKIKKN YLETTVEKTI DNLKALMKN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GIM3 GIM4 GIM5 PAC10 PFD1 YKE2
    View Details Krogan NJ, et al. (2006) GIM3 GIM4 GIM5 PAC10 PFD1 YKE2
    View Details Qiu et al. (2008) GIM3 PAC10 PFD1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen VPS5 PFD1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PFD1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle