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Protein Overview: PAN6

General Information:
Name(s) found: PAN6 / YIL145C [SGD]
Description(s) found:
Found 10 descriptions.
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  • Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: pantothenate biosynthetic process [IMPLink to PubMed article]
    Molecular Function: pantoate-beta-alanine ligase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNISRCSVHI YVYKKWCVLI LHCFIQVFIL HIHIELMKIF HTVEEVVQWR TQELRETRFR  60
   61 ETIGFVPTMG CLHSGHASLI SQSVKENTYT VVSIFVNPSQ FAPTEDLDNY PRTLPDDIKL 120
  121 LESLKVDVLF APNAHVMYPQ GIPLDIEEQK GPFVSVLGLS EKLEGKTRPN FFRGVATVVT 180
  181 KLFNIVMADV AYFGQKDIQQ FIVLQCMVDE LFVNTRLQMM PIVRNNNGLA LSSRNKYLCP 240
  241 ESLKISENLY RGLKAAENAI RRLAPGGRLS RSEIIDTVTQ IWAPYVDSHD FKIDYVSLAD 300
  301 FKTLDELSDV ENTSEQQPIV ISCAVYVTDR EKPDTVVRLI DNIVI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] PSI-BLAST 561.9691 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)
    2 View Details [223..345] PSI-BLAST 561.9691 Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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