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Protein Overview: ICE2

General Information:
Name(s) found: ICE2 / YIL090W [SGD]
Description(s) found:
Found 22 descriptions.
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  • Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 491 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed articleLink to PubMed article]
    Biological Process: endoplasmic reticulum organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSLSKSFMQ SGRICAACFY LLFTLLSIPI SFKVGGLECG LSFTVTLFTL YFITTTLNVL  60
   61 ARRHGGRLYI FFTNCLYYSQ HFIIASLLYL FLSGFSNDEL GNVLKNKYNE SESFLEALKN 120
  121 SLNSNQINYV LYYYYYRFVV QPWQFVLTKS TPFFTLSEGF FTILAIQAVG ETNRWLSNDL 180
  181 NSNTWIISSL LTSGGVITAS LYYLYRIYVT PIWPLSIQTA SLLGLVLSMV CGLGLYGIVS 240
  241 QKGSVIESSL FFAYIVRCIY EISPKLATTA TDEILNLFKD VWQKHQRNLP TADNLLCYFH 300
  301 NVILKNAEVL WGSFIPRGRK KTGDFHDKLI SILSFEKVSL ISKPFWKFFK NFTFSVPLSI 360
  361 NEFCQVTIKM ASESVSPAIV INLCFRVLMF YSATRIIPAL QRKNDKQLRK SRRIMKGLYW 420
  421 YSPCILIAMY THLILQYSGE LKKDLCIWGC SEKWFGVDQP EIIVDSWGFW NWCNIFCTIL 480
  481 VYATELIGSG S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ICE2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..491] deduced N/A No confident structure predictions are available.
    2 View Details [359..491] FFAS03 0.989 HCN2J 443-645 in the presence of cGMP


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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