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Protein Overview: CBR1

General Information:
Name(s) found: CBR1 / YIL043C [SGD]
Description(s) found:
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  • gi|740968|prf||2006246A cytochrome b reductase [NCBI NR]
  • ref|NP_012221.1| Cbr1p [Saccharomyces cerevisiae] [NCBI NR]
  • gi|600005|emb|CAA86908.1| cytochrome b5 reductase [Saccharomyces cerevisiae] [NCBI NR]
  • gi|585542|sp|P38626|NCB5R_YEAST Putative NADH-cytochrome b5 reductase (P35) [NCBI NR]
  • gi|461338|emb|CAA82214.1| cytochrome b5 reductase [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S49935 cytochrome-b5 reductase (EC 1.6.2.2) - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Putative NADH-cytochrome b5 reductase - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot]
  • (P38626) Putative NADH-cytochrome b5 reductase (EC 1.6.2.2) (P35) [Swiss-Prot]
  • CBR1 cytochrome-b5 reductase EC:1.6.2.2 [mips]
  • Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia [SGD]
  • CBR1, Chr IX from 274071-275039, reverse complement [yeast_orfs2]
  • Chr IX from 274071-275039, reverse complement [yeastorf3.fasta]
  • Chr IX from 275039-274071, reverse complement [yeastorf5.fasta]
  • CBR1 SGDID:S0001305, Chr IX from 275039-274071, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Cbr1p [Saccharomyces cerevisiae]gi|600005|emb|CAA86908.1| cytochrome b5 reductase [Saccharomyces cerevisiae]gi|461338|emb|CAA82214.1| cytochrome b5 reductase [Saccharomyces cerevisiae]gi|585542|sp|P38626|NC5R_YEAST Putative NADH-cytochrome b5 reductase [nrdb_11152004_Chlamydomonas]
  • CBR1 SGDID:S000001305, Chr IX from 275039-274071, reverse complement, Verified ORF, "Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • cytochrome b reductase [nr-271106-contam.fasta]
  • Putative NADH-cytochrome b5 reductase (P35) [nr-271106-contam.fasta]
  • cytochrome b5 reductase [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 322 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    microsome [IDALink to PubMed article]
    mitochondrial outer membrane [IDALink to PubMed article]
    Biological Process: electron transport [IDALink to PubMed article]
    Molecular Function: cytochrome-b5 reductase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKYSYYIRR KNEREKKVLK VCIQLALQQE TQSIKQSKMA IDAQKLVVVI VIVVVPLLFK  60
   61 FIIGPKTKPV LDPKRNDFQS FPLVEKTILT HNTSMYKFGL PHADDVLGLP IGQHIVIKAN 120
  121 INGKDITRSY TPTSLDGDTK GNFELLVKSY PTGNVSKMIG ELKIGDSIQI KGPRGNYHYE 180
  181 RNCRSHLGMI AGGTGIAPMY QIMKAIAMDP HDTTKVSLVF GNVHEEDILL KKELEALVAM 240
  241 KPSQFKIVYY LDSPDREDWT GGVGYITKDV IKEHLPAATM DNVQILICGP PAMVASVRRS 300
  301 TVDLGFRRSK PLSKMEDQVF VF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..72] PSI-BLAST 9.39794 2Fe-2S ferredoxin
    2 View Details [73..174] PSI-BLAST 469.9897 Nitrate reductase core domain; Nitrate reductase
    3 View Details [175..322] PSI-BLAST 469.9897 Nitrate reductase core domain; Nitrate reductase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle