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Protein Overview: MNT3

General Information:
Name(s) found: MNT3 / YIL014W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: protein amino acid O-linked glycosylation [IDALink to PubMed article]
    Molecular Function: alpha-1,3-mannosyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKSLKSRRL ILKRLVTLLL SLFFSYLIFS ASRNVTSSNK LNNHASERTA VESSAFNWIE  60
   61 KRQHQVRSEN LMNRLSAYFL PFLSRSSHKE RVLLRQLGNN EIAKSDKCRY IFEVLYKIDP 120
  121 DWDNAQTAKF YNVDGVDNTL ASLLGERLRS YDYCFLSGQL DPTAIFANST VNPHDLQNRM 180
  181 FPFLKKINEE SKTVMWPIIT DMTTGEAVPA PEVDMESSNF NGNFWSNWNR LSKGRGFVLT 240
  241 IAEKDVPLFL KQLKVMEFSK NELPFQIVST GNELSAESIA KISETAKETE QRVYLVDCST 300
  301 VLDTNFANTY ISFFQNKWVA TLFNTFEEYI LLDADVVPFV GSDYFFDSPS YRESGILLFK 360
  361 DRVMENEQTF QYCIEMLNEV EPSAQERRFI GSRLVFDSSL PFSSETSEEA SVYYNFFKKL 420
  421 RLHHVDSGLV VVNKLEKLNG LLMSFMLNLD GKLQRCVYGD KEIFWLGQLY AGQDYSINPV 480
  481 DGSIIGPVNE EPENDDGHKS GMYYICSTQI AHSDSKNRLL WVNGGLKTCK ISNSAEDDFG 540
  541 REPEYFKSRY GDISKLKRIY DASLNVEGLI VPDVSVHPWM QIKECSNYMY CAYATGDGHT 600
  601 NSELDEGRLI TFTEKELRYI NDISRTWNAN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #34 Asynchronous SPB prep Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] deduced N/A No confident structure predictions are available.
    2 View Details [221..384] ORFEUS 7.92 Galactosyltransferase LgtC
    3 View Details [385..630] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • mannosyltransferase activity
    		•  2.72970569728159 bayes_pls_golite062009
  • transferase activity
    		•  2.3313878748424 bayes_pls_golite062009
  • catalytic activity
    		•  1.73979371332125 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  1.64579615957842 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.58983046450767 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  1.18238034321908 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  0.539883035270389 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  0.373609073759347 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.218795796569067 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  0.130891646999536 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle