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Protein Overview: AMA1

General Information:
Name(s) found: AMA1 / YGR225W [SGD]
Description(s) found:
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  • ref|NP_011741.2| Ama1p [Saccharomyces cerevisiae] [NCBI NR]
  • AMA1 meiosis-specific regulator of the anaphase promoting complex/cyclosome [mips]
  • Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis [SGD]
  • AMA1, Chr VII from 945138-946320,946414-946919 [yeast_orfs2]
  • Chr VII from 945138-946320,946414-946919 [yeastorf3.fasta]
  • Chr VII from 945145-946327,946421-946926 [yeastorf4.fasta]
  • AMA1 SGDID:S0003457, Chr VII from 945146-946328,946422-946927, Verified ORF [yeastflysequest.fasta]
  • AMA1 SGDID:S0003457, Chr VII from 945148-946330,946424-946929, Verified ORF [10112005cervSGD.fasta]
  • Ama1p [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas]
    • Organism: Saccharomyces cerevisiae
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: anaphase-promoting complex [IPILink to PubMed article]
    Biological Process: ascospore formation [IMPLink to PubMed article]
    protein catabolic process [IMPLink to PubMed article][IPILink to PubMed article]
    ascospore wall assembly [IMPLink to PubMed article]
    meiosis I [IEPLink to PubMed article][IMPLink to PubMed article]
    Molecular Function: enzyme activator activity [IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPHLYHRY NSKSSNKNIN SSGNSTEVDR FIPKSVSRNA YKSIPMLNGF DISYSELCEK  60
   61 SPSPERLSSP EFFNELRNTG HYESISTTNE FSMSSISSSS ESQVTRSGSA RASRNDYSKL 120
  121 TKEQKDHRKN IAHSLGFQLP DRVFTFETTS AEILEKNKAI KNCFGPGSCA EIRSTFDFST 180
  181 LSPDVARYYI ANSNARSASP QRQIQRPAKR VKSHIPYRVL DAPCLRNDFY SNLISWSRTT 240
  241 NNVLVGLGCS VYIWSEKEGA VSILDHQYLS EKRDLVTCVS FCPYNTYFIV GTKFGRILLY 300
  301 DQKEFFHSSN TNEKEPVFVF QTESFKGICC LEWFKPGEIC KFYVGEENGN VSLFEIKSLH 360
  361 FPIKNWSKRQ KLEDENLIGL KLHSTYQAQA QQVCGISLNE HANLLAVGGN DNSCSLWDIS 420
  421 DLDKPIKKFV LPHKAAVKAI AFCPWSKSLL ATGGGSKDRC IKFWHTSTGT LLDEICTSGQ 480
  481 VTSLIWSLRH KQIVATFGFG DTKNPVLITL YSYPKLSKLL EVRSPNPLRV LSAVISPSSM 540
  541 AICVATNDET IRFMNCGTIR RK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] deduced N/A No confident structure predictions are available.
    2 View Details [99..464] PSI-BLAST 46.30103 Tup1, C-terminal domain
    3 View Details [465..562] PSI-BLAST 65.0 beta1-subunit of the signal-transducing G protein heterotrimer


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle