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Protein Overview: SHY1

General Information:
Name(s) found: SHY1 / YGR112W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 389 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    integral to membrane [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    Molecular Function: unfolded protein binding [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLGARSTY RWFSIAASIP TKNAIGKSTY LLASRNQQYR GIITSTVDWK PIKTGKSPND  60
   61 DSRRERSFGK KIVLGLMFAM PIISFYLGTW QVRRLKWKTK LIAACETKLT YEPIPLPKSF 120
  121 TPDMCEDWEY RKVILTGHFL HNEEMFVGPR KKNGEKGYFL FTPFIRDDTG EKVLIERGWI 180
  181 SEEKVAPDSR NLHHLSLPQE EHLKVVCLVR PPKKRGSLQW AKKDPNSRLW QVPDIYDMAR 240
  241 SSGCTPIQFQ ALYDMKDHPI IEEHTRNEAS QNNSTSSLWK FWKREPTTAV NGTQAVDNNT 300
  301 SKPRSRQEMP TDQTIEFDER QFIKAGVPIG RKPTIDLKNN HLQYLVTWYG LSFLSTIFLI 360
  361 VALRKAKRGG VVSQDQLMKE KLKHSRKYM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered #17 Mitotic Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SHY1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..389] Pfam 293.49485 SURF1 family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle