Protein Overview: ORM1

General Information:
Name(s) found:	ORM1 / YGR038W [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Evolutionarily conserved protein, similar to Orm2p, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control [SGD]
Organism:	Saccharomyces cerevisiae
Length:	222 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	response to unfolded protein [IMP][ISS]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTELDYQGTA EAASTSYSRN QTDLKPFPSA GSASSSIKTT EPVKDHRRRR SSSIISHVEP  60
   61 ETFEDENDQQ LLPNMNATWV DQRGAWIIHV VIIILLKLFY NLFPGVTTEW SWTLTNMTYV 120
  121 IGSYVMFHLI KGTPFDFNGG AYDNLTMWEQ IDDETLYTPS RKFLISVPIA LFLVSTHYAH 180
  181 YDLKLFSWNC FLTTFGAVVP KLPVTHRLRI SIPGITGRAQ IS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	TIM50	No Comments	Hazbun TR, et al. (2003)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	ECM29	ORM1	1	Unpublished Fields Lab Data
View Screen	RAD10	ORM1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	ORM1	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..222]	MSA	10.014957	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2