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Protein Overview: MNT2

General Information:
Name(s) found: MNT2 / YGL257C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: protein amino acid O-linked glycosylation [IDALink to PubMed article]
    Molecular Function: alpha-1,3-mannosyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRKNRLFIL VVLLGIVLVV YYSQLNSLDL VEPVQSSSSG NGGCWSYYEG LTPGWLNDFY  60
   61 DVNQITPNPA KDVIELVTRI KIFFNCLQQV DGHNIQRLRD IEKKLFPYIN FEKLETDESA 120
  121 FWHTTTRWNG EVYHASMLEF DPKNHQFLRS KPINFDTGLS FWENWLHTVT QSGSKGIVIS 180
  181 ASDVQLNETI RLLKVLRFIK NDYPIQIVHN ADLSQDSMKS IIKYARSLDT AEYPAQELWF 240
  241 LNVHSLLNPK YSKKFTTYSN KWLALTFSSF EIPILMDSDT VPFVSIEKFY ELEEFQKTGV 300
  301 LFFKDRVISD DLFESSELKI LREIVYGCIG LDLEDESKIH EQVEDPVVAQ VLENMFIKKY 360
  361 KHHLESGLVI LHKGKHLFSM LTSIALQFSP IAEYFHGDKD FFWLGELLSN NRFTFHPVDA 420
  421 SNIGQLGNVV SKESTGEFYQ ICSVQLSHTD RDGSLLWLNG GLNICKKTSW EYDYEHRQRL 480
  481 NDMFQNADEL REYYASPVKL EGIIIPDTSI SGWINSGECF LFNYCTLFKE GEFGKLIKFK 540
  541 EDEKLRLSQI VDIWNKDI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] deduced N/A No confident structure predictions are available.
    2 View Details [130..305] ORFEUS 7.75 Glycogenin
    3 View Details [306..558] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • mannosyltransferase activity
    		•  2.72970569728159 bayes_pls_golite062009
  • transferase activity
    		•  2.3313878748424 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.31282143022166 bayes_pls_golite062009
  • catalytic activity
    		•  1.73979371332125 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  1.64579615957842 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.58983046450767 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  1.18238034321908 bayes_pls_golite062009
  • binding
    		•  0.809446708810115 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  0.373609073759347 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.355405833568127 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  0.130891646999536 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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