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Protein Overview: YGL185C

General Information:
Name(s) found: YGL185C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Putative protein with sequence similarity to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: metabolic process [ISSLink to PubMed article]
    Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDSPATTGK PTILFIADPC ETSATLNSKA FKEKFRILRY QLDTKEAFLN FLERHEQDKI  60
   61 CAIYAGFPAF KKIGGMTRSI IEHKSFPRKN LKCIVLCSRG YDGWDLDTLR KHEIRLYNYQ 120
  121 DDENEKLIDD LKLHQVGNDV ADCALWHILE GFRKFSYYQK LSRETGNTLT ARAKAAEKSG 180
  181 FAFGHELGNM FAESPRGKKC LILGLGSIGK QVAYKLQYGL GMEIHYCKRS EDCTMSQNES 240
  241 WKFHLLDETI YAKLYQFHAI VVTLPGTPQT EHLINRKFLE HCNPGLILVN LGRGKILDLR 300
  301 AVSDALVTGR INHLGLDVFN KEPEIDEKIR SSDRLTSITP HLGSATKDVF EQSCELALTR 360
  361 ILRVVSGEAA SDEHFSRVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MLC1 YGL185C 1 Unpublished Fields Lab Data
    View Screen SPT21 YGL185C 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YGL185C Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135]
    [346..379]    		 PSI-BLAST 203.69897 D-glycerate dehydrogenase
    2 View Details [136..345] PSI-BLAST 203.69897 D-glycerate dehydrogenase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle