YRC Public Data Repository - Protein Structure Prediction

Protein:	YGL185C
Organism:	Saccharomyces cerevisiae
Length:	379 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGL185C.

Description	E-value	Query Range	Subject Range
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1 GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...	6.0E-91	[9..379]	[1..326]
gi\|14601656, gi\|... - gi\|5105521\|dbj\|BAA80834.1\| 347aa long hypothetical D-3-phosphoglycerate dehydrogenase [Aeropyrum per... gi\|7431353 - pir\|\|E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 - Aeropyrum pernix (strain K1)	6.0E-91	[6..379]	[11..340]
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	8.0E-90	[12..375]	[3..312]
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus GN=gyaR PE=3 SV=1 GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=gyaR ...	3.0E-89	[9..379]	[1..326]
gi\|16758046, gi\|... - gi\|16758046\|ref\|NP_445787.1\| C-terminal binding protein 2 [Rattus norvegicus], gi\|149061321\|gb\|EDM11...	3.0E-85	[9..377]	[575..903]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /... SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1	6.0E-85	[11..375]	[1..312]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	7.0E-84	[9..378]	[2..316]
gi\|18858481, gi\|... - gi\|18858481\|ref\|NP_571790.1\| C-terminal binding protein 2 [Danio rerio], gi\|11933135\|dbj\|BAB19679.1\|...	1.0E-83	[9..377]	[32..360]
gi\|28372481, gi\|... - gi\|28372481\|ref\|NP_783643.1\| C-terminal binding protein 2 [Bos taurus], gi\|12034659\|gb\|AAG45953.1\|AF...	7.0E-83	[9..377]	[569..897]

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Predicted Domain #1

Region A:
Residues: [1-135]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDSPATTGK PTILFIADPC ETSATLNSKA FKEKFRILRY QLDTKEAFLN FLERHEQDKI  60
   61 CAIYAGFPAF KKIGGMTRSI IEHKSFPRKN LKCIVLCSRG YDGWDLDTLR KHEIRLYNYQ 120
  121 DDENEKLIDD LKLHQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [346-379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKDVFEQSCE LALTRILRVV SGEAASDEHF SRVV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	203.69897
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [136-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGNDVADCAL WHILEGFRKF SYYQKLSRET GNTLTARAKA AEKSGFAFGH ELGNMFAESP  60
   61 RGKKCLILGL GSIGKQVAYK LQYGLGMEIH YCKRSEDCTM SQNESWKFHL LDETIYAKLY 120
  121 QFHAIVVTLP GTPQTEHLIN RKFLEHCNPG LILVNLGRGK ILDLRAVSDA LVTGRINHLG 180
  181 LDVFNKEPEI DEKIRSSDRL TSITPHLGSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	203.69897
Match:	1gdhA_
Description:	D-glycerate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits