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Protein Overview: PRM8

General Information:
Name(s) found: PRM8 / YGL053W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Pheromone-regulated protein with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: conjugation with cellular fusion [IEPLink to PubMed article]
    response to pheromone [IEPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTPSENTNA KSDSLDEPGA YLIEENVALP KDIFHSYLSY WIYEAAHCTP VMLLSLVIGV  60
   61 LISIIILFHD NENCVGVSVG FLLIFSGILV IVLILRFGPQ ISDEDFKCKL LMEIITRKPT 120
  121 VKGKEWRTIT YKMNQYLFDN DLWNTPYYFY RDEDCHRYFL SLIKGRTFKK QKESSASNVK 180
  181 DAQSNDETAG TPNEAAESSS FSAGPNFIKL LTKAAEIEQQ FQKEYWRQEY PGVDEFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PRM8 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..237] Pfam 58.408935 DUP family No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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