Protein Overview: YGL039W

General Information:
Name(s) found:	YGL039W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6321399\|ref\|NP_011476.1\| Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol); Ygl039wp [Saccharomyce [NCBI NR] gi\|51012981\|gb\|AAT92784.1\| YGL039W [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S64041 probable membrane protein YGL039w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1723822\|sp\|P53183.1\|YGD9_YEAST RecName: Full=Putative uncharacterized oxidoreductase YGL039W [NCBI NR] gi\|1322522\|emb\|CAA96741.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Putative uncharacterized oxidoreductase YGL039W OS=Saccharomyces cerevisiae GN=YGL039W PE=1 SV=1 [Swiss-Prot] Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol) [mips] Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols [SGD] YGL039W, Chr VII from 423958-425004 [yeast_orfs2] Chr VII from 423958-425004 [yeastorf3.fasta] Chr VII from 423965-425011 [yeastorf4.fasta] (P53183) Hypothetical 38.3 kDa protein in HEM2-OCH1 intergenic region [4932.FASTACCERV.txt] YGL039W SGDID:S0003007, Chr VII from 423965-425011, Verified ORF [yeastflysequest.fasta] YGL039W SGDID:S0003007, Chr VII from 423967-425013, Verified ORF [10112005cervSGD.fasta] Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol) [Saccharomyces cerevisiae]gi\|51012981\|gb\|AAT92784. [nrdb_11152004_Chlamydomonas] YGL039W SGDID:S000003007, Chr VII from 423967-425013, Verified ORF, "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2 [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YGL039W SGDID:S000003007, Chr VII from 423967-425013, Verified ORF, "Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols" [yeast-200209-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YGL039W [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol); Ygl039wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Putative uncharacterized oxidoreductase YGL039W [nr-271106-contam.fasta] YGL039W SGDID:S000003007, Chr VII from 423967-425013, Verified ORF, "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)" [yeast-contam_custom.fasta] [chemostatdb.fasta] Putative uncharacterized oxidoreductase YGL039W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGL039W PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YGL039W SGDID:S000003007, Chr VII from 423961-425007, Genome Release 64-1-1, Verified ORF, "Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols" [yeast-030211-contam.fasta] YGL039W SGDID:S000003007, Chr VII from 423961-425007, Genome Release 64-2-1, Verified ORF, "Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols" [20141208_orf_trans.fasta]
Organism:	Saccharomyces cerevisiae
Length:	348 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	telomere maintenance [IMP]
Molecular Function:	oxidoreductase activity [IDA] dihydrokaempferol 4-reductase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTEKTVVFV SGATGFIALH VVDDLLKTGY KVIGSGRSQE KNDGLLKKFK SNPNLSMEIV  60
   61 EDIAAPNAFD KVFQKHGKEI KVVLHIASPV HFNTTDFEKD LLIPAVNGTK SILEAIKNYA 120
  121 ADTVEKVVIT SSVAALASPG DMKDTSFVVN EESWNKDTWE SCQANAVSAY CGSKKFAEKT 180
  181 AWDFLEENQS SIKFTLSTIN PGFVFGPQLF ADSLRNGINS SSAIIANLVS YKLGDNFYNY 240
  241 SGPFIDVRDV SKAHLLAFEK PECAGQRLFL CEDMFCSQEA LDILNEEFPQ LKGKIATGEP 300
  301 GSGSTFLTKN CCKCDNRKTK NLLGFQFNKF RDCIVDTASQ LLEVQSKS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		AVO2 PMU1 YER064C YGL039W YTA12
View Details	Gavin AC, et al. (2006)		OLA1 SLM3 YGL039W

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	YGL039W	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..89] [100..131] [174..199] [250..266]	PSI-BLAST	104.0	dTDP-glucose 4,6-dehydratase (RmlB)
2	View Details	[90..99] [132..173] [200..210] [235..249] [267..277] [305..335]	PSI-BLAST	104.0	dTDP-glucose 4,6-dehydratase (RmlB)
3	View Details	[211..234] [278..304] [336..348]	PSI-BLAST	104.0	dTDP-glucose 4,6-dehydratase (RmlB)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.87

Protein Overview: YGL039W

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: