Protein Overview: ERP6

General Information:
Name(s) found:	ERP6 / YGL002W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6321436\|ref\|NP_011513.1\| Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Erp6p [Saccharo [NCBI NR] pir\|\|S64004 probable membrane protein YGL002w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1723794\|sp\|P53198.1\|ERP6_YEAST RecName: Full=Protein ERP6; Flags: Precursor [NCBI NR] gi\|1322449\|emb\|CAA96702.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Protein ERP6 OS=Saccharomyces cerevisiae GN=ERP6 PE=1 SV=1 [Swiss-Prot] ERP6 Member of the p24 family involved in ER to Golgi transport [mips] Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD] ERP6, Chr VII from 494512-495162 [yeast_orfs2] Chr VII from 494512-495162 [yeastorf3.fasta] Chr VII from 494519-495169 [yeastorf4.fasta] (P53198) ERP6 protein precursor [4932.FASTACCERV.txt] ERP6 SGDID:S0002970, Chr VII from 494519-495169, Verified ORF [yeastflysequest.fasta] ERP6 SGDID:S0002970, Chr VII from 494521-495171, Verified ORF [10112005cervSGD.fasta] Erp6p [Saccharomyces cerevisiae]gi\|1322449\|emb\|CAA96702.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132517\|pir\|\|S64004 probable membrane protein YGL002w - yeast (Saccharomyces cerevisiae)gi\|1723794\|sp\|P53198\|ERP6_YEAST ERP6 protein precurs [nrdb_11152004_Chlamydomonas] ERP6 SGDID:S000002970, Chr VII from 494521-495171, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] ERP6 SGDID:S000002970, Chr VII from 494521-495171, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in hi [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; Erp6p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Protein ERP6 precursor [nr-271106-contam.fasta] ERP6 SGDID:S000002970, Chr VII from 494521-495171, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Protein ERP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERP6 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] ERP6 SGDID:S000002970, Chr VII from 494517-495167, Genome Release 64-1-1, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [yeast-030211-contam.fasta] ERP6 SGDID:S000002970, Chr VII from 494517-495167, Genome Release 64-2-1, Verified ORF, "Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication" [20141208_orf_trans.fasta] TR2632\|c0_g1_i1\|g.1967 ORF TR2632\|c0_g1_i1\|g.1967 TR2632\|c0_g1_i1\|m.1967 type:complete len:217 (+) TR2632\|c0_g1_i1:117-767(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR6494\|c0_g1_i1\|g.4693 ORF TR6494\|c0_g1_i1\|g.4693 TR6494\|c0_g1_i1\|m.4693 type:complete len:217 (+) TR6494\|c0_g1_i1:204-854(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YGL002W SGDID:S000002970, Chr VII from 494517-495167, Genome Release 64-1-1, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_1415\|g.1281 ORF asmbl_1415\|g.1281 asmbl_1415\|m.1281 type:complete len:217 (+) asmbl_1415:203-853(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_1465\|g.956 ORF asmbl_1465\|g.956 asmbl_1465\|m.956 type:complete len:217 (+) asmbl_1465:117-767(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_1420\|g.1098 ORF ID=asmbl_1420\|g.1098 ID=asmbl_1420\|m.1098 type:complete len:217 (+) ID=asmbl_1420:203-853(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_1475\|g.1077 ORF ID=asmbl_1475\|g.1077 ID=asmbl_1475\|m.1077 type:complete len:217 (+) ID=asmbl_1475:117-767(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	216 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA ] integral to membrane [ISS]
Biological Process:	secretory pathway [IGI][IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSHYIFLAF VLLPFRVSAF YFYGYGGDRK CFLKELSKDT LLKGSYNLEV YDDKLADYAL  60
   61 PSYNDYGIVI DVEEVFDNNH RVVHQQGSPS GDFSFLALES GEYKICLQSR VNNWVGKTKT 120
  121 KLEIEFEVGF EAMLDMQRKE TLESLHGKVS ILNSKIVDIR REQQLMRERE ESFRDISESV 180
  181 NSRAMWWTVT QVTLLIIICV WQMKSLRSFF VKQKVL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	CTF13	ERP6	1	Unpublished Fields Lab Data
View Screen	SPT21	ERP6	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..216]	Pfam	98.21467	emp24/gp25L/p24 family/GOLD No confident structure predictions are available.
2	View Details	[142..216]	MSA	6.211995	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2