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Protein Overview: PES4

General Information:
Name(s) found: PES4 / YFR023W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 611 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSISNKKPS ILSMVPLNIL KNQDLKVKKD QEKKISFNPV VTPIRPDDYH EKTSRSSSSS  60
   61 HSDSPEFLRI NNNKSGHKNG KLKSFESKKL VPLFIGDLHE TVTEETLKGI FKKYPSFVSA 120
  121 KVCLDSVTKK SLGHGYLNFE DKEEAEKAME ELNYTKVNGK EIRIMPSLRN TTFRKNFGTN 180
  181 VFFSNLPLNN PLLTTRVFYD TFSRYGKILS CKLDSRKDIG FVYFEDEKTA RNVIKMYNNT 240
  241 SFFGKKILCG IHFDKEVRSV PNFETQKSRL DAETIIEKEQ SLNEKHSKGN DKESKNIYSS 300
  301 SQNSIFIKNL PTITTRDDIL NFFSEVGPIK SIYLSNATKV KYLWAFVTYK NSSDSEKAIK 360
  361 RYNNFYFRGK KLLVTRAQDK EERAKFIESQ KISTLFLENL SAVCNKEFLK YLCHQENIRP 420
  421 FKIQIDGYDE NSSTYSGFIK FRNFEDATRI FNFLNNRLVG GSIVTTSWER QNNAPKYHDG 480
  481 YGMRNIHTSS HPQITPYYQY SHANSLNSPH MRDLSSMNSS TRSLIKNKNF NKKVLETFEK 540
  541 QVRRGIDFMR FPSATRDENV HGIAEYIFDT YWNRDVLILD KFLSLLNSSP YHEGVLQKQI 600
  601 EEAASSLGFK R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] MSA 2.439995 View MSA. Confident ab initio structure predictions are available.
    2 View Details [77..176] PSI-BLAST 312.927757 Poly(A)-binding protein
    3 View Details [177..273] PSI-BLAST 10.221849 Nucleolin
    4 View Details [274..377] PSI-BLAST 38.228787 CBP20, 20KDa nuclear cap-binding protein
    5 View Details [378..510] PSI-BLAST 86.056057 Nuclear ribonucleoprotein A1 (RNP A1, UP1)
    6 View Details [511..611] MSA 5.049993 View MSA. Confident ab initio structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle