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Protein Overview: YFL052W

General Information:
Name(s) found: YFL052W [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 465 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: DNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARNRQACDC CCIRRVKCDR KKPCKCCLQH NLQCTYLRPL KKRGPKPVKV RNLKKVDDVQ  60
   61 VFSKSSSGGI MKVPKALIDQ CLRLYNDKLY VIWPLLCYDD LYELLEKRYD ETCVYWFLVS 120
  121 LSAATLSDLQ TEIESEGGVT FTGIQLSSFC MSSRQEFDDF NGSDIFKIMT YYCLNRCYAQ 180
  181 MSNSRTSYRL SCEAVGLIKL AGFHREETLK LLPFDEQQLG RKVYYLLLLT ERYFSVYTHC 240
  241 ATSLDTTIAP PQPENVTDPR LSLDSFLEMI RVFTVPGKCF FDALATDSAN VTCTEDSLKK 300
  301 IWRELHTVPL EIEPWSYGYV DISFSRHWIR TLAWKLVLQI SGMRISFLSN SKNTHIPVEI 360
  361 ARDMLEDTFL IPKNLYAVHG PGISVKALEI ADALVDVVNQ YDQNAESEAW NFLFDISKFV 420
  421 FSLKHCDSTL VDKFTTKCQC ALITLPLSNP LESTDGSKED VDALP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..43] PSI-BLAST 36.221849 Gal4; CD2-Gal4
    2 View Details [44..350] MSA 41.138997 View MSA. No confident structure predictions are available.
    3 View Details [351..465] deduced N/A No confident structure predictions are available.
    4 View Details [315..465] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  4.56444258780502 bayes_pls_golite062009
  • DNA binding
    		•  4.26146437716972 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.17369933547911 bayes_pls_golite062009
  • transcription factor activity
    		•  3.049435548132 bayes_pls_golite062009
  • binding
    		•  2.91929847152301 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.03201524223606 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.87955444697212 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.86200506906385 bayes_pls_golite062009
  • transcription activator activity
    		•  0.915626626047549 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle