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Protein Overview: ALR2

General Information:
Name(s) found: ALR2 / YFL050C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 858 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IMPLink to PubMed article]
    Biological Process: di-, tri-valent inorganic cation transport [IMPLink to PubMed article][ISSLink to PubMed article]
    magnesium ion transport [IDALink to PubMed article]
    Molecular Function: di-, tri-valent inorganic cation transmembrane transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSLSTSFDS SSDLPRSKSV DNTAASMKTG KYPKLENYRQ YSDAQPIRHE ALALKVDETK  60
   61 DSRHKFSSSN GENSGVENGG YVEKTNISTS GRMDFEGEAE AEAVKRYQLR SFALLSSNAR 120
  121 PSRLAKSETH QKQIHVESIA PSLPKNAALE RGHDTALPAG TSSNRCNLEA SSSARTFTSA 180
  181 RKASLVSAIF ETSAESEHGT HPKQAKLKRR TYSTISTHSS VNPTTLLTRT ASQKSDMGND 240
  241 TRRIKPLRMD SRVSFHSEIS QASRDSQETE EDVCFPMFRL LHTRVNGVDF DELEEYAQIS 300
  301 NAERNLSLAN HQRHSERTYN HTDQDTGFTN SASTSGSSAA LKYTPEISRT LEKNCSVNEM 360
  361 YVSENNESVR EDDKPDLHPD VTFGRNKIEG EKEGNDSSYS RAYYTLQNTE YQIPSRFSFF 420
  421 RSESDETVHA SDIPSLISEG QTFYELFKGG DPTWWLDCSC PTDDEMRCIA KTFGIHPLTA 480
  481 EDIRMQETRE KVELFKSYYF VCFHTFENDK ESENYLEPIN VYIVVFRSGV LTFHFDPISH 540
  541 CANVRRRVRQ LRDYVSVNSD WLCYALIDDI TDSFAPVIQS IEYEADSIDD SVFMTRDMDF 600
  601 AAMLQRIGES RRKTMTLMRL LSGKADVIKM FAKRCQDETN GIGPVLKSQT NMVNLQAEQE 660
  661 NVNQNNSNNQ ISLSNSYMQT TSQPRGDIAL YLGDIQDHLL TMFQNLLAYE KIFSRSHANY 720
  721 LAQLQVESFN SNNKVTEMLG KVTMLGTMLV PLNVITGLFG MNVKVPGRNG SIAWWYGILG 780
  781 VLLLLAVISW FLASYWIKKI DPPATLNEAA GSGAKSVISS FLPKRDKRFN DDSKNGNARV 840
  841 GVRRKSTVSL PSRYSRYN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ALR2 CTR3

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..372] deduced N/A No confident structure predictions are available.
    2 View Details [373..554] MSA 1.094989 View MSA. No confident structure predictions are available.
    3 View Details [555..701] ORFEUS 7.94 alpha-actinin
    4 View Details [702..858] MSA 1.105989 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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