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Protein Overview: OXA1

General Information:
Name(s) found: OXA1 / YER154W [SGD]
Description(s) found:
Found 30 descriptions.
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  • Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 402 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: protein insertion into mitochondrial membrane from inner side [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    Molecular Function: membrane insertase activity [IMPLink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKLTSRLVT SRFAASSRLA TARTIVLPRP HPSWISFQAK RFNSTGPNAN DVSEIQTQLP  60
   61 SIDELTSSAP SLSASTSDLI ANTTQTVGEL SSHIGYLNSI GLAQTWYWPS DIIQHVLEAV 120
  121 HVYSGLPWWG TIAATTILIR CLMFPLYVKS SDTVARNSHI KPELDALNNK LMSTTDLQQG 180
  181 QLVAMQRKKL LSSHGIKNRW LAAPMLQIPI ALGFFNALRH MANYPVDGFA NQGVAWFTDL 240
  241 TQADPYLGLQ VITAAVFISF TRLGGETGAQ QFSSPMKRLF TILPIISIPA TMNLSSAVVL 300
  301 YFAFNGAFSV LQTMILRNKW VRSKLKITEV AKPRTPIAGA SPTENMGIFQ SLKHNIQKAR 360
  361 DQAERRQLMQ DNEKKLQESF KEKRQNSKIK IVHKSNFINN KK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) OXA1 TIM22 TIM44

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data OXA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] deduced N/A No confident structure predictions are available.
    2 View Details [93..335] Pfam 10.337242 60Kd inner membrane protein No confident structure predictions are available.
    3 View Details [336..402] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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