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Protein Overview: COM2

General Information:
Name(s) found: COM2 / YER130C [SGD]
Description(s) found:
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  • gi|6320977|ref|NP_011056.1| hypothetical protein; Yer130cp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|1723598|sp|P39959.2|YEW0_YEAST RecName: Full=Zinc finger protein YER130C [NCBI NR]
  • gi|1384129|gb|AAC03228.1| Yer130cp [Saccharomyces cerevisiae] [NCBI NR]
  • Zinc finger protein YER130C OS=Saccharomyces cerevisiae GN=YER130C PE=2 SV=2 [Swiss-Prot]
  • Similarity to Msn2p and weak similarity to Msn4p [mips]
  • Protein of unknown function [SGD]
  • YER130C, Chr V from 421111-422442, reverse complement [yeast_orfs2]
  • Chr V from 421111-422442, reverse complement [yeastorf3.fasta]
  • Chr V from 422442-421111, reverse complement [yeastorf5.fasta]
  • (P39959) Putative 50.3 kDa zinc finger protein in PAK1-RPS26B intergenic region [4932.FASTACCERV.txt]
  • YER130C SGDID:S0000932, Chr V from 422442-421111, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Yer130cp [Saccharomyces cerevisiae]gi|1384129|gb|AAC03228.1| Yer130cp [Saccharomyces cerevisiae]gi|1723598|sp|P39959|YEW0_YEAST Putative 50.3 kDa zinc finger protein in PAK1-RPS26B intergenic region [nrdb_11152004_Chlamydomonas]
  • YER130C SGDID:S000000932, Chr V from 422442-421111, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YER130C SGDID:S000000932, Chr V from 422442-421111, reverse complement, Uncharacterized ORF, "Protein of unknown function" [yeast-200209-contam.fasta]
  • hypothetical protein; Yer130cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Zinc finger protein YER130C [nr-271106-contam.fasta]
  • Yer130cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Zinc finger protein YER130C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YER130C PE=2 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YER130C SGDID:S000000932, Chr V from 422446-421115, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Protein of unknown function; transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; the C. Albicans homolog (MNL1) plays a role in adaptation to stress" [yeast-030211-contam.fasta]
  • Zinc finger protein YER130C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YER130C PE=4 SV=2 [YEAST.fasta.20131015]
  • COM2 SGDID:S000000932, Chr V from 422446-421115, Genome Release 64-2-1, reverse complement, Verified ORF, "Transcription factor that binds IME1 Upstream Activation Signal (UAS)ru; COM2 transcription is regulated by Haa1p, Sok2p and Zap1p transcriptional activators; may bind the IME1 promoter under all growth conditions to negatively regulate its transcription in the absence of a positive regulator that binds more effectively; repressor activity may depend on phosphorylation by PKA; C. albicans homolog (MNL1) plays a role in adaptation to stress" [20141208_orf_trans.fasta]
  • Zinc finger protein YER130C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YER130C PE=3 SV=2 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 443 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLYPLQRFE SNDTVFSYTL NSKTELFNES RNNDKQHFTL QLIPNANANA KEIDNNNVEI  60
   61 INDLTGNTIV DNCVTTATSS NQLERRLSIS DYRTENGNYY EYEFFGRREL NEPLFNNDIV 120
  121 ENDDDIDLNN ESDVLMVSDD ELEVNERFSF LKQQPLDGLN RISSTNNLKN LEIHEFIIDP 180
  181 TENIDDELED SFTTVPQSKK KVRDYFKLNI FGSSSSSNNN SNSLGCEPIQ TENSSSQKMF 240
  241 KNRFFRSRKS TLIKSLPLEQ ENEVLINSGF DVSSNEESDE SDHAIINPLK LVGNNKDIST 300
  301 QSIAKTTNPF KSGSDFKMIE PVSKFSNDSR KDLLAAISEP SSSPSPSAPS PSVQSSSSSH 360
  361 GLVVRKKTGS MQKTRGRKPS LIPDASKQFG CEFCDRRFKR QEHLKRHVRS LHMCEKPFTC 420
  421 HICNKNFSRS DNLNQHVKTH ASL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) COM2 RTA1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] MSA 31.144996 View MSA. No confident structure predictions are available.
    2 View Details [178..235] PSI-BLAST 125.035458 ZIF268
    3 View Details [236..342] deduced N/A No confident structure predictions are available.
    4 View Details [343..443] PSI-BLAST 2.09691 Tramtrack protein (two zinc-finger peptide)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle