Protein Overview: FCY2

General Information:
Name(s) found:	FCY2 / YER056C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|729467\|sp\|P17064.2\|FCY2_YEAST RecName: Full=Purine-cytosine permease FCY2; Short=PCP FCY2; AltName: Full=Cytosine/purine transport protein FCY2; AltName: Full=Fluorocytosine resistance protein 2 [NCBI NR] gi\|6320897\|ref\|NP_010976.1\| Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; Fcy2p [Saccharomyces cerevisiae] [NCBI NR] gi\|603292\|gb\|AAB64592.1\| Fcy2p: purine-cytosine permease [Saccharomyces cerevisiae] [NCBI NR] pir\|\|GRBYCP cytosine/purine transport protein - yeast (Saccharomyces cerevisiae) [NCBI NR] Purine-cytosine permease FCY2 OS=Saccharomyces cerevisiae GN=FCY2 PE=1 SV=2 [Swiss-Prot] FCY2 Purine/cytosine permease [mips] Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation [SGD] FCY2, Chr V from 266511-268112, reverse complement [yeast_orfs2] Chr V from 266511-268112, reverse complement [yeastorf3.fasta] Chr V from 268112-266511, reverse complement [yeastorf5.fasta] (P17064) Purine-cytosine permease (PCP) (Cytosine/purine transport protein) [4932.FASTACCERV.txt] FCY2 SGDID:S0000858, Chr V from 268112-266511, reverse complement, Verified ORF [yeastflysequest.fasta] Fcy2p [Saccharomyces cerevisiae]gi\|729467\|sp\|P17064\|FCY2_YEAST Purine-cytosine permease (PCP) (Cytosine/purine transport protein)gi\|1070658\|pir\|\|GRBYCP cytosine/purine transport protein - yeast (Saccharomyces cerevisiae)gi\|603292\|gb\|AAB64592.1\| Fcy2p: [nrdb_11152004_Chlamydomonas] FCY2 SGDID:S000000858, Chr V from 268112-266511, reverse complement, Verified ORF, "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Purine-cytosine permease FCY2 (PCP FCY2) (Cytosine/purine transport protein FCY2) (Fluorocytosine resistance protein 2) [nr-271106-contam.fasta] Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; Fcy2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Fcy2p: purine-cytosine permease [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Purine-cytosine permease FCY2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FCY2 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] FCY2 SGDID:S000000858, Chr V from 268113-266512, Genome Release 64-1-1, reverse complement, Verified ORF, "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" [yeast-030211-contam.fasta] FCY2 SGDID:S000000858, Chr V from 268113-266512, Genome Release 64-2-1, reverse complement, Verified ORF, "Purine-cytosine permease; mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation; relative distribution to the vacuole increases upon DNA replication stress" [20141208_orf_trans.fasta] YER056C SGDID:S000000858, Chr V from 268113-266512, Genome Release 64-1-1, reverse complement, Verified ORF, "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	533 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [IDA]
Biological Process:	cytidine transport [IDA][IMP] AMP metabolic process [IDA] cytosine transport [IDA] purine transport [IDA]
Molecular Function:	cytidine transmembrane transporter activity [IDA][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEEGNNVYE IQDLEKRSPV IGSSLENEKK VAASETFTAT SEDDQQYIVE SSEATKLSWF  60
   61 HKFFASLNAE TKGVEPVTED EKTDDSILNA ASMWFSANMV IASYALGALG PMVFGLNFGQ 120
  121 SVLVIIFFNI MGLIFVAFFS VFGAELGLRQ MILSRYLVGN VTARIFSLIN VIACVGWGIV 180
  181 NTSVSAQLLN MVNEGSGHVC PIWAGCLIII GGTVLVTFFG YSVIHAYEKW SWVPNFAVFL 240
  241 VIIAQLSRSG KFKGGEWVGG ATTAGSVLSF GSSIFGFAAG WTTYAADYTV YMPKSTNKYK 300
  301 IFFSLVAGLA FPLFFTMILG AASAMAALND PTWKAYYDKN AMGGVIYAIL VPNSLNGFGQ 360
  361 FCCVLLALST IANNIPNMYT VALSAQALWA PLAKIPRVVW TMAGNAATLG ISIPATYYFD 420
  421 GFMENFMDSI GYYLAIYIAI SCSEHFFYRR SFSAYNIDDW DNWEHLPIGI AGTAALIVGA 480
  481 FGVALGMCQT YWVGEIGRLI GKYGGDIGFE LGASWAFIIY NILRPLELKY FGR

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		FCY2 FUI1 FUN26 FUR4

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	FCY2	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..72]	deduced	N/A	No confident structure predictions are available.
2	View Details	[73..533]	Pfam	152.455932	Permease for cytosine/purines, uracil, thiamine, allantoin No confident structure predictions are available.
3	View Details	[446..533]	deduced	N/A	No confident structure predictions are available.

Protein Overview: FCY2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: