YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: HSP31

General Information:
Name(s) found: HSP31 / YDR533C [SGD]
Description(s) found:
Found 35 descriptions.
SHOW ALL
  • Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: cysteine-type peptidase activity [ISSLink to PubMed article]
    unfolded protein binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKKVLLAL TSYNDVFYSD GAKTGVFVVE ALHPFNTFRK EGFEVDFVSE TGKFGWDEHS  60
   61 LAKDFLNGQD ETDFKNKDSD FNKTLAKIKT PKEVNADDYQ IFFASAGHGT LFDYPKAKDL 120
  121 QDIASEIYAN GGVVAAVCHG PAIFDGLTDK KTGRPLIEGK SITGFTDVGE TILGVDSILK 180
  181 AKNLATVEDV AKKYGAKYLA PVGPWDDYSI TDGRLVTGVN PASAHSTAVR SIDALKN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HSP31 SNO4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HSP31 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..237] PSI-BLAST 32.69897 Intracellular protease

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.761311388604334 bayes_pls_golite062009
  • binding
    		•  0.674707430307546 bayes_pls_golite062009
  • ligase activity
    		•  0.314215307503825 bayes_pls_golite062009
  • hydrolase activity
    		•  0.132707384514464 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle