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Protein Overview: HLR1

General Information:
Name(s) found: HLR1 / YDR528W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENLCPPPPS QMKDFSTPPR NRHRHKRSFA ISGDFEFLKQ PASAPVLPSA YDSPTFENTP  60
   61 RRVSGMSVTM PDESQNESAL LNSPSPRFFI SEASTYSSPI KGVPDAIINL DDVLINKPKM 120
  121 CRSHRKTKSV PVKLDEFYSS HKCSSVPELT INEEIDEDDT NPQLLEPVKP LSSTSLSTDM 180
  181 NEDKKMTLKN ARSHNSLKIQ AQKQRYYNSA RYLPLNSEDR ATDPQILTKQ SSVTSLFSSR 240
  241 SITPVSCNIN NAGRINAISG NYLDDVLYDL DTPATTLIQD IDNLQTSINE RVRLSPQSSS 300
  301 IKKYFSKDGK SVSSFNFQSQ ECDMVSFTED FAHVTSLSSS ILDSEKQTDD EEEESIPEEI 360
  361 LRGEPLHVYN ETSGSDKSVI LPTKQKSAPI NKDSKHSSTQ YEEKSFKKNR KFKIFAKLFC 420
  421 TRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data HLR1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..308] MSA 1.002903 View MSA. No confident structure predictions are available.
    2 View Details [309..423] deduced N/A No confident structure predictions are available.
    3 View Details [325..423] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle