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Protein Overview: BCS1

General Information:
Name(s) found: BCS1 / YDR375C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the incorporation of the Rip1p and Qcr10p subunits into the cytochrome bc(1) complex; member of the CDC48/PAS1/SEC18 ATPase family [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 456 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed article]
    mitochondrial inner membrane [IDALink to PubMed article]
    Biological Process: chaperone-mediated protein complex assembly [IMPLink to PubMed article][IPILink to PubMed article]
    aerobic respiration [IMPLink to PubMed article]
    Molecular Function: ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKPIDIQY DKQATPNLSG VITPPTNETG NDSVREKLSK LVGDAMSNNP YFAAGGGLMI  60
   61 LGTGLAVARS GIIKASRVLY RQMIVDLEIQ SKDKSYAWFL TWMAKHPQRV SRHLSVRTNY 120
  121 IQHDNGSVST KFSLVPGPGN HWIRYKGAFI LIKRERSAKM IDIANGSPFE TVTLTTLYRD 180
  181 KHLFDDILNE AKDIALKTTE GKTVIYTSFG PEWRKFGQPK AKRMLPSVIL DSGIKEGILD 240
  241 DVYDFMKNGK WYSDRGIPYR RGYLLYGPPG SGKTSFIQAL AGELDYNICI LNLSENNLTD 300
  301 DRLNHLMNNM PERSILLLED IDAAFNKRSQ TGEQGFHSSV TFSGLLNALD GVTSSEETIT 360
  361 FMTTNHPEKL DAAIMRPGRI DYKVFVGNAT PYQVEKMFMK FYPGETDICK KFVNSVKELD 420
  421 ITVSTAQLQG LFVMNKDAPH DALKMVSSLR NANHIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data BCS1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] deduced N/A No confident structure predictions are available.
    2 View Details [167..388] PSI-BLAST 188.927757 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    3 View Details [389..456] PSI-BLAST 188.927757 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.24

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle