YRC Public Data Repository - Protein Structure Prediction

Protein:	BCS1
Organism:	Saccharomyces cerevisiae
Length:	456 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BCS1.

Description	E-value	Query Range	Subject Range
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	0.0	[4..452]	[295..774]
gi\|7435762, gi\|5... - pir\|\|D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay), gi... gi\|5458778, gi\|1... - gi\|5458778\|emb\|CAB50265.1\| ATPase of the AAA+ family [Pyrococcus abyssi GE5], gi\|14521559\|ref\|NP_127...	0.0	[4..447]	[295..769]
gi\|18977335, gi\|... - gi\|18977335\|ref\|NP_578692.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18893012...	0.0	[4..452]	[292..771]
gi\|151942348 - gi\|151942348\|gb\|EDN60704.1\| ATPase (AAA family) [Saccharomyces cerevisiae YJM789] BCS1 - Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required f... gi\|207346377 - gi\|207346377\|gb\|EDZ72889.1\| YDR375Cp-like protein [Saccharomyces cerevisiae AWRI1631] BCS1_YEAST - Mitochondrial chaperone BCS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCS1 PE=1 S...	0.0	[1..456]	[1..456]
gi\|7435750 - pir\|\|B69512 cell division control protein 48, AAA family (cdc48-2) homolog - Archaeoglobus fulgidus gi\|2648442, gi\|1... - gi\|2648442\|gb\|AAB89157.1\| cell division control protein 48, AAA family (cdc48-2) [Archaeoglobus fulg...	0.0	[3..453]	[277..762]
gi\|6513847 - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis] gi\|57640604, gi\|... - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis], gi\|57640604\|ref\|YP_183082.1\| cell d...	0.0	[4..451]	[292..769]
gi\|18313875, gi\|... - gi\|18313875\|ref\|NP_560542.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[4..453]	[260..694]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKPIDIQY DKQATPNLSG VITPPTNETG NDSVREKLSK LVGDAMSNNP YFAAGGGLMI  60
   61 LGTGLAVARS GIIKASRVLY RQMIVDLEIQ SKDKSYAWFL TWMAKHPQRV SRHLSVRTNY 120
  121 IQHDNGSVST KFSLVPGPGN HWIRYKGAFI LIKRERSAKM IDIANG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [167-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPFETVTLTT LYRDKHLFDD ILNEAKDIAL KTTEGKTVIY TSFGPEWRKF GQPKAKRMLP  60
   61 SVILDSGIKE GILDDVYDFM KNGKWYSDRG IPYRRGYLLY GPPGSGKTSF IQALAGELDY 120
  121 NICILNLSEN NLTDDRLNHL MNNMPERSIL LLEDIDAAFN KRSQTGEQGF HSSVTFSGLL 180
  181 NALDGVTSSE ETITFMTTNH PEKLDAAIMR PGRIDYKVFV GN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	188.927757
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [389-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATPYQVEKMF MKFYPGETDI CKKFVNSVKE LDITVSTAQL QGLFVMNKDA PHDALKMVSS  60
   61 LRNANHIF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	188.927757
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits