YRC Public Data Repository - Protein Structure Prediction

Protein:	BCS1
Organism:	Saccharomyces cerevisiae
Length:	456 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BCS1.

Description	E-value	Query Range	Subject Range
gi\|3257095, gi\|1... - gi\|3257095\|dbj\|BAA29778.1\| 840aa long hypothetical cell division control protein (transitional endop... gi\|7435754 - pir\|\|H71114 probable cell division control protein (transitional endoplasmic reticulum ATPase) - Pyr...	0.0	[4..452]	[295..774]
gi\|7435762, gi\|5... - pir\|\|D75046 transitional endoplasmic reticulum atpase PAB1478 - Pyrococcus abyssi (strain Orsay), gi... gi\|5458778, gi\|1... - gi\|5458778\|emb\|CAB50265.1\| ATPase of the AAA+ family [Pyrococcus abyssi GE5], gi\|14521559\|ref\|NP_127...	0.0	[4..447]	[295..769]
gi\|18977335, gi\|... - gi\|18977335\|ref\|NP_578692.1\| cell division protein CDC48 [Pyrococcus furiosus DSM 3638], gi\|18893012...	0.0	[4..452]	[292..771]
gi\|151942348 - gi\|151942348\|gb\|EDN60704.1\| ATPase (AAA family) [Saccharomyces cerevisiae YJM789] BCS1 - Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required f... gi\|207346377 - gi\|207346377\|gb\|EDZ72889.1\| YDR375Cp-like protein [Saccharomyces cerevisiae AWRI1631] BCS1_YEAST - Mitochondrial chaperone BCS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCS1 PE=1 S...	0.0	[1..456]	[1..456]
gi\|7435750 - pir\|\|B69512 cell division control protein 48, AAA family (cdc48-2) homolog - Archaeoglobus fulgidus gi\|2648442, gi\|1... - gi\|2648442\|gb\|AAB89157.1\| cell division control protein 48, AAA family (cdc48-2) [Archaeoglobus fulg...	0.0	[3..453]	[277..762]
gi\|6513847 - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis] gi\|57640604, gi\|... - gi\|6513847\|dbj\|BAA87866.1\| Pk-cdcA [Thermococcus kodakaraensis], gi\|57640604\|ref\|YP_183082.1\| cell d...	0.0	[4..451]	[292..769]
gi\|18313875, gi\|... - gi\|18313875\|ref\|NP_560542.1\| AAA family ATPase, CDC48 subfamily protein [Pyrobaculum aerophilum str....	0.0	[4..453]	[260..694]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKPIDIQY DKQATPNLSG VITPPTNETG NDSVREKLSK LVGDAMSNNP YFAAGGGLMI  60
   61 LGTGLAVARS GIIKASRVLY RQMIVDLEIQ SKDKSYAWFL TWMAKHPQRV SRHLSVRTNY 120
  121 IQHDNGSVST KFSLVPGPGN HWIRYKGAFI LIKRERSAKM IDIANG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [167-388]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPFETVTLTT LYRDKHLFDD ILNEAKDIAL KTTEGKTVIY TSFGPEWRKF GQPKAKRMLP  60
   61 SVILDSGIKE GILDDVYDFM KNGKWYSDRG IPYRRGYLLY GPPGSGKTSF IQALAGELDY 120
  121 NICILNLSEN NLTDDRLNHL MNNMPERSIL LLEDIDAAFN KRSQTGEQGF HSSVTFSGLL 180
  181 NALDGVTSSE ETITFMTTNH PEKLDAAIMR PGRIDYKVFV GN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	188.927757
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [389-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATPYQVEKMF MKFYPGETDI CKKFVNSVKE LDITVSTAQL QGLFVMNKDA PHDALKMVSS  60
   61 LRNANHIF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	188.927757
Match:	1e32A_
Description:	Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits