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Protein Overview: EXG2

General Information:
Name(s) found: EXG2 / YDR261C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed article]
    Biological Process: cellular cell wall organization [ICLink to PubMed article]
    Molecular Function: glucan 1,3-beta-glucosidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLKSFFFSA FLVLCLSKFT QGVGTTEKEE SLSPLELNIL QNKFASYYAN DTITVKGITI  60
   61 GGWLVTEPYI TPSLYRNATS LAKQQNSSSN ISIVDEFTLC KTLGYNTSLT LLDNHFKTWI 120
  121 TEDDFEQIKT NGFNLVRIPI GYWAWKQNTD KNLYIDNITF NDPYVSDGLQ LKYLNNALEW 180
  181 AQKYELNVWL DLHGAPGSQN GFDNSGERIL YGDLGWLRLN NTKELTLAIW RDMFQTFLNK 240
  241 GDKSPVVGIQ IVNEPLGGKI DVSDITEMYY EAFDLLKKNQ NSSDNTTFVI HDGFQGIGHW 300
  301 NLELNPTYQN VSHHYFNLTG ANYSSQDILV DHHHYEVFTD AQLAETQFAR IENIINYGDS 360
  361 IHKELSFHPA VVGEWSGAIT DCATWLNGVG VGARYDGSYY NTTLFTTNDK PVGTCISQNS 420
  421 LADWTQDYRD RVRQFIEAQL ATYSSKTTGW IFWNWKTEDA VEWDYLKLKE ANLFPSPFDN 480
  481 YTYFKADGSI EEKFSSSLSA QAFPRTTSSV LSSTTTSRKS KNAAISNKLT TSQLLPIKNM 540
  541 SLTWKASVCA LAITIAALCA SL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data EXG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334]
    [357..375]
    [442..457]    		 PSI-BLAST 855.30103 Exo-beta-(1,3)-glucanase
    2 View Details [335..356]
    [376..441]
    [458..498]    		 PSI-BLAST 855.30103 Exo-beta-(1,3)-glucanase
    3 View Details [499..562] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, acting on glycosyl bonds
    		•  5.36248919165223 bayes_pls_golite062009
  • glucan 1,3-beta-glucosidase activity
    		•  5.16200085143699 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • glucosidase activity
    		•  3.69195576225095 bayes_pls_golite062009
  • beta-glucosidase activity
    		•  3.14931331494576 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • alpha-amylase activity
    		•  2.09193270404736 bayes_pls_golite062009
  • amylase activity
    		•  2.03484942782894 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • hydrolase activity
    		•  1.22608062881808 bayes_pls_golite062009
  • binding
    		•  1.08189849662259 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.763360027922833 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.34612220294711 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  0.263065978664289 bayes_pls_golite062009
  • hyalurononglucosaminidase activity
    		•  0.123700697143861 bayes_pls_golite062009
  • pattern binding
    		•  0.113396113487931 bayes_pls_golite062009
  • receptor binding
    		•  0.0577582382963624 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle