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Protein Overview: CTH1

General Information:
Name(s) found: CTH1 / YDR151C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 325 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: cellular iron ion homeostasis [IGILink to PubMed article]
    transcription [ISSLink to PubMed article]
    Molecular Function: transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMPNVAPNSY YLNIPNANST STTTSSIFSD LNKEYESKIK EIEEYYIKTL LNENTDNDDS  60
   61 SSSEGHNINE TDILSEYSPR PSPWLPSKPN CYHPLGDFKD LIISDSRPTN TLPINNPFAG 120
  121 NNNISTLATT EKKRKKRSLE VEINPTYTTS AFSLPLTAEN LQKLSQVDSQ STGLPYTLPI 180
  181 QKTTKLEPCR RAPLQLPQLV NKTLYKTELC ESFTIKGYCK YGNKCQFAHG LNELKFKKKS 240
  241 NNYRTKPCIN WSKLGYCPYG KRCCFKHGDD KDVEIYQNAN DGRSKDTALT PLPTSLAPSN 300
  301 NDNITNLSKP RNLHTSVKAL QRMTW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CAB1 CTH1 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..325] ORFEUS 9.3 RBP1
    2 View Details [198..325] PSI-BLAST 25.30103 Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle