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Protein Overview: PTP1

General Information:
Name(s) found: PTP1 / YDL230W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 335 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: protein amino acid dephosphorylation [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein tyrosine phosphatase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAPWYIRQ RDTDLLGKFK FIQNQEDGRL REATNGTVNS RWSLGVSIEP RNDARNRYVN  60
   61 IMPYERNRVH LKTLSGNDYI NASYVKVNVP GQSIEPGYYI ATQGPTRKTW DQFWQMCYHN 120
  121 CPLDNIVIVM VTPLVEYNRE KCYQYWPRGG VDDTVRIASK WESPGGANDM TQFPSDLKIE 180
  181 FVNVHKVKDY YTVTDIKLTP TDPLVGPVKT VHHFYFDLWK DMNKPEEVVP IMELCAHSHS 240
  241 LNSRGNPIIV HCSAGVGRTG TFIALDHLMH DTLDFKNITE RSRHSDRATE EYTRDLIEQI 300
  301 VLQLRSQRMK MVQTKDQFLF IYHAAKYLNS LSVNQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen INP52 PTP1 2 Unpublished Fields Lab Data
    View Screen RHO4 PTP1 1 Unpublished Fields Lab Data
    View Screen UBC7 PTP1 1 Unpublished Fields Lab Data
    View Screen YIF1 PTP1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PTP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..335] PSI-BLAST 394.502279 RPTP Lar


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle