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Protein Overview: SCM3

General Information:
Name(s) found: SCM3 / YDL139C [SGD]
Description(s) found:
Found 14 descriptions.
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  • Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; contains nuclear export signal (NES); required for G2/M progression and localization of Cse4p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 247 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQMIYKQKV GYSISTPPLQ INRRMKTNKK ISKRRSLKNL HGALKGLLKE SGKKSESKIR  60
   61 KHSDCNPVHR VYPPNIEKRK TKKDDGISRP IAERNGHVYI MSKENHIIPK LTDDEVMERH 120
  121 KLADENMRKV WSNIISKYES IEEQGDLVDL KTGEIVEDNG HIKTLTANNS TKDKRTKYTS 180
  181 VLRDIIDISD EEDGDKNDEY TLWANDSEAS DSEVDADNDT EEEKDEKLID ADFKKYEAKL 240
  241 SKRILRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..247] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle