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Protein Overview: GIT1

General Information:
Name(s) found: GIT1 / YCR098C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 518 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: glycerophosphodiester transport [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: glycerophosphodiester transmembrane transporter activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKDITSVN EKEVNENTNP RIIKYDAERR ATRTETSKKD KWKNIVTIIA SGFALISDGY  60
   61 VNGSMSMLNK VFVMEYGKKN YSSKVSTRVS NAALVGIIFG QFFMGIAADY YSRKSCILVA 120
  121 TAILVIGSAL CAASHGTTVP GMFWMLTVMR GLVGIGVGAE YPTSTLSANE SANEYTTTKR 180
  181 GGILVMVTNL PLAFGGPFAT IIFLIVYKIC SGTKHLEAIW RTVFAIGCFW PLSVFYFRWK 240
  241 TATTEVYEKG RIKRNIPYFL ALKFYWKRLL GTCGTWFMYD FVTFPNGIFS STIISSVIKD 300
  301 QNDLVKVAEW NLLLGVLAVL GVPIGAYLSD RIGRKYTLMF GFSGYIIFGL IIGCAYDQLK 360
  361 KITPLFIIFY AFMNMLGNAG PGDMLGVISS EASATAVRGV FYGLSAVTGK IGSVVGVECF 420
  421 QPIRDNLGAR WTFIIAAICG LIGIIITYFF VPHSLESDLM KQDVEFHNYL VSNGWTGKMG 480
  481 FDETDEESMV RTIEVEENGT NCSKKNAEII SVRQVDQS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ARR3 GIT1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..518] PSI-BLAST 75.30103 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.21742729128468 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.31748220369305 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.74166040263114 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.60627834007397 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.3426261924492 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  2.98462343619844 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.17838823008408 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • binding
    		•  0.805286077372817 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle