Protein Overview: VAC17

General Information:
Name(s) found:	VAC17 / YCL063W [SGD]
Description(s) found: Found 23 descriptions. SHOW ALL	Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	423 amino acids
Gene Ontology:
Cellular Component:	vacuolar membrane [IDA]
Biological Process:	vacuole inheritance [IEP][IGI][IMP][IPI]
Molecular Function:	protein anchor [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATQALEDIT ERLLIRSQEA ILQLDLWIQR QQRSSICQTT DQESLDKLSQ QYNQYMSQLN  60
   61 SLYVRSESVR DKLSKEQQRR LITEDNEHQR IEDLVREFQD ITLRLNELAT VPNEAPNDSP 120
  121 QSQSTRSSLG SFQPRPLKII ERQRLCMVTP SKPPKKSVGF NPINEVDCPS KTNSLPCSPK 180
  181 KQPARNRTLR AAKSHDTGLN KSKKPSSSDT YESFFKNRQR LSLTFFDEMD DEDFDSDQDT 240
  241 IILPNISTPP HVGVTAKGAE FEPLRRYNSH ESILSNKPAP SKSLNLGSFS ASFFRPSNPT 300
  301 FGTSISNVQV NCHPTVAATM APSRNGPRIS SSKALLSSFI ARSDTHTVKE NNTNLKHASF 360
  361 MDKFNSSLST ISESFQSKRG RKNKGMNEER ISNHNVAQEQ KNNMDISVSI EELQDALNTE 420
  421 LLF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		LCD1 VAC17

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	PAN1	No Comments	Toshima J, et al (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	THG1	VAC17	1	Hazbun TR, et al. (2003)
View Screen	RPC19	VAC17	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..148]	MSA	1.002946	View MSA. Confident ab initio structure predictions are available.
2	View Details	[149..206]	deduced	N/A	No confident structure predictions are available.
3	View Details	[207..423]	MSA	1.002903	View MSA. No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2