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Protein Overview: LRE1

General Information:
Name(s) found: LRE1 / YCL051W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 583 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [TASLink to PubMed article]
    Biological Process: response to heat [IDALink to PubMed article]
    cellular cell wall organization [IGILink to PubMed article]
    Molecular Function: transcription regulator activity [IDALink to PubMed article]
    protein kinase inhibitor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNTHTQHVQ ISEPNPVNTL STPSKRGHRH RRSLAISGDF DFLKQPAAIV NLPPPQAAEN  60
   61 CPSTAPTAVS STLSPIRYNR FPCKTNEDAG TLDLPEPRFY PLSPKNNLQT PSPRFFISEE 120
  121 PSFSSPVKGV PDAIINLDDA LKTRPRSFKS HRRSESAPPD LEVMVDKGNC AAGSNSMIKE 180
  181 EEDSLIEPES KNEYYEQKLP TALLSPLRPS LCVSEQAIDV DDSALNGSPT HHNHGMQNAN 240
  241 ARNSNTFNSL KIKGQKQRYY HYTKQLPLTV GCDSQSPKEQ RSAASMTINQ AMTPSSLAYT 300
  301 PSKLASTPAT PVSFYDSNAD INLESDNFPL KDNPRYAKDG YPKKCGNSQL NRVLDSDKRQ 360
  361 DFSGESRRRR SGSPISHMQH RNLIDNMKGR RNSNTINSIF NYKSQHYEMP YDDMMKNENI 420
  421 NAQSMPFSVN GVNNENSIGG VITRADDAPL QHSVVKSCTP DGKEEMNRLK SNDSNEYSKS 480
  481 EGQIRTNSQL SKDILMGEPG DMVDLSSFVN AQRKASNETG DLVFSLSQDD DALKTFHASN 540
  541 SAATSNESWC ISDDALGKQA QDSEVRRKRK SKLGLFRHIF SRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..325] MSA 1.002914 View MSA. No confident structure predictions are available.
    2 View Details [326..583] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle