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Protein Overview: MMS4

General Information:
Name(s) found: MMS4 / YBR098W [SGD]
Description(s) found:
Found 13 descriptions.
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  • Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 471 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISSLink to PubMed article]
    Holliday junction resolvase complex [IDALink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    reciprocal meiotic recombination [IGILink to PubMed article]
    DNA topological change [IGILink to PubMed article]
    response to DNA damage stimulus [IMPLink to PubMed article]
    Molecular Function: transcription coactivator activity [IDALink to PubMed article]
    endonuclease activity [IDALink to PubMed article]
    crossover junction endodeoxyribonuclease activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQIVDFVED KDSRNDASIQ IIDGPSNVEI IALSESMDQD ECKRAHVSSA EMIPSSPQRK  60
   61 SVSNDVENVD LNKSIELSAP FFQDISISKL DDFSTTVNSI IDSSLRNENN AKGNAKKLLD 120
  121 DLISDEWSAD LESSGKKHNK SQYNLRDIAE KWGVQSLKNP EPIAVDCEYK TQGIGKTNSD 180
  181 ISDSPKSQIG AADILFDFPL SPVKHENPTE EKHNSIANEN SSPDNSLKPA GKQNHGEDGT 240
  241 SMAKRVYNKG EDEQEHLPKG KKRTIALSRT LINSTKLPDT VELNLSKFLD SSDSITTDVL 300
  301 STPAKGSNIV RTGSQPIFSN ANCFQEAKRS KTLTAEDPKC TKNTAREVSQ LENYIAYGQY 360
  361 YTREDSKNKI RHLLKENKNA FKRVNQIYRD NIKARSQMII EFSPSLLQLF KKGDSDLQQQ 420
  421 LAPAVVQSSY NDSMPLLRFL RKCDSIYDFS NDFYYPCDPK IVEENRFDSI L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..471] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle